Diffuse large B-cell lymphoma presenting as LUTS: Clinical practice points

There is a paucity of management recommendations for patients with aggressive Diffuse large B cell lymphoma (DLBCL) of the bladder. A 57-year-old male patient presented with lower urinary tract symptoms underwent flexible cystoscopy and then bladder tumor biopsy. Through immediate staging CT scan, t...

Full description

Bibliographic Details
Main Authors: Soum D. Lokeshwar, Syed N. Rahman, Jamil Syed, Thomas F. Monaghan, Benjamin Press, Mark S. Soloway
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Urology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214442021003338
_version_ 1818461733132435456
author Soum D. Lokeshwar
Syed N. Rahman
Jamil Syed
Thomas F. Monaghan
Benjamin Press
Mark S. Soloway
author_facet Soum D. Lokeshwar
Syed N. Rahman
Jamil Syed
Thomas F. Monaghan
Benjamin Press
Mark S. Soloway
author_sort Soum D. Lokeshwar
collection DOAJ
description There is a paucity of management recommendations for patients with aggressive Diffuse large B cell lymphoma (DLBCL) of the bladder. A 57-year-old male patient presented with lower urinary tract symptoms underwent flexible cystoscopy and then bladder tumor biopsy. Through immediate staging CT scan, tumor and bone biopsies he was diagnosed with a 16 cm Stage IVa high-grade DLBCL. He was treated with DA EPOCH with only a partial response and was transitioned to R-ICE. For rarer presentations of bladder cancer during diagnostic cystoscopy there should be no delay in tumor imaging and involving medical oncology in early treatment decision making.
first_indexed 2024-12-14T23:50:50Z
format Article
id doaj.art-a7f31778e8ec426ca9155b5d8ddfab3a
institution Directory Open Access Journal
issn 2214-4420
language English
last_indexed 2024-12-14T23:50:50Z
publishDate 2022-01-01
publisher Elsevier
record_format Article
series Urology Case Reports
spelling doaj.art-a7f31778e8ec426ca9155b5d8ddfab3a2022-12-21T22:43:16ZengElsevierUrology Case Reports2214-44202022-01-0140101893Diffuse large B-cell lymphoma presenting as LUTS: Clinical practice pointsSoum D. Lokeshwar0Syed N. Rahman1Jamil Syed2Thomas F. Monaghan3Benjamin Press4Mark S. Soloway5Department of Urology, Yale School of Medicine, New Haven, CT, USADepartment of Urology, Yale School of Medicine, New Haven, CT, USA; Corresponding author. Department of Urology, Yale School of Medicine, 20 York Street, CT, 06511, USA.Department of Urology, Yale School of Medicine, New Haven, CT, USADepartment of Urology, University of Texas Southwestern, Dallas, TX, USADepartment of Urology, Yale School of Medicine, New Haven, CT, USAUrologic Oncology, Memorial Physician Group, Division of Urology, Memorial Healthcare System, Aventura, FL, USAThere is a paucity of management recommendations for patients with aggressive Diffuse large B cell lymphoma (DLBCL) of the bladder. A 57-year-old male patient presented with lower urinary tract symptoms underwent flexible cystoscopy and then bladder tumor biopsy. Through immediate staging CT scan, tumor and bone biopsies he was diagnosed with a 16 cm Stage IVa high-grade DLBCL. He was treated with DA EPOCH with only a partial response and was transitioned to R-ICE. For rarer presentations of bladder cancer during diagnostic cystoscopy there should be no delay in tumor imaging and involving medical oncology in early treatment decision making.http://www.sciencedirect.com/science/article/pii/S2214442021003338Bladder cancerLymphomaCystoscopy
spellingShingle Soum D. Lokeshwar
Syed N. Rahman
Jamil Syed
Thomas F. Monaghan
Benjamin Press
Mark S. Soloway
Diffuse large B-cell lymphoma presenting as LUTS: Clinical practice points
Urology Case Reports
Bladder cancer
Lymphoma
Cystoscopy
title Diffuse large B-cell lymphoma presenting as LUTS: Clinical practice points
title_full Diffuse large B-cell lymphoma presenting as LUTS: Clinical practice points
title_fullStr Diffuse large B-cell lymphoma presenting as LUTS: Clinical practice points
title_full_unstemmed Diffuse large B-cell lymphoma presenting as LUTS: Clinical practice points
title_short Diffuse large B-cell lymphoma presenting as LUTS: Clinical practice points
title_sort diffuse large b cell lymphoma presenting as luts clinical practice points
topic Bladder cancer
Lymphoma
Cystoscopy
url http://www.sciencedirect.com/science/article/pii/S2214442021003338
work_keys_str_mv AT soumdlokeshwar diffuselargebcelllymphomapresentingaslutsclinicalpracticepoints
AT syednrahman diffuselargebcelllymphomapresentingaslutsclinicalpracticepoints
AT jamilsyed diffuselargebcelllymphomapresentingaslutsclinicalpracticepoints
AT thomasfmonaghan diffuselargebcelllymphomapresentingaslutsclinicalpracticepoints
AT benjaminpress diffuselargebcelllymphomapresentingaslutsclinicalpracticepoints
AT markssoloway diffuselargebcelllymphomapresentingaslutsclinicalpracticepoints