Sentinel Lymph Node Biopsy : A new approach in the management of head and neck cancers
Cervical lymph node metastasis affects the prognosis and overall survival rate of and therapeutic planning for patients with head and neck squamous cell carcinomas (HNSCCs). However, advanced diagnostic modalities still lack accuracy in detecting occult neck metastasis. A sentinel lymph node biopsy...
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| Format: | Article |
| Language: | English |
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Sultan Qaboos University
2017-10-01
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| Series: | Sultan Qaboos University Medical Journal |
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| Online Access: | https://journals.squ.edu.om/index.php/squmj/article/view/1809 |
| _version_ | 1818752504514478080 |
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| author | Deepti Sharma George Koshy Sonal Grover |
| author_facet | Deepti Sharma George Koshy Sonal Grover |
| author_sort | Deepti Sharma |
| collection | DOAJ |
| description | Cervical lymph node metastasis affects the prognosis and overall survival rate of and therapeutic planning for patients with head and neck squamous cell carcinomas (HNSCCs). However, advanced diagnostic modalities still lack accuracy in detecting occult neck metastasis. A sentinel lymph node biopsy is a minimally invasive auxiliary method for assessing the presence of occult metastatic disease in a patient with a clinically negative neck. This technique increases the specificity of neck dissection and thus reduces morbidity among oral cancer patients. The removal of sentinel nodes and dissection of the levels between the primary tumour and the sentinel node or the irradiation of target nodal basins is favoured as a selective treatment approach; this technique has the potential to become the new standard of care for patients with HNSCCs. This article presents an update on clinical applications and novel developments in this field. |
| first_indexed | 2024-12-18T04:52:31Z |
| format | Article |
| id | doaj.art-a7f9ae897bb14e00a0e6502de7c796f2 |
| institution | Directory Open Access Journal |
| issn | 2075-051X 2075-0528 |
| language | English |
| last_indexed | 2024-12-18T04:52:31Z |
| publishDate | 2017-10-01 |
| publisher | Sultan Qaboos University |
| record_format | Article |
| series | Sultan Qaboos University Medical Journal |
| spelling | doaj.art-a7f9ae897bb14e00a0e6502de7c796f22022-12-21T21:20:23ZengSultan Qaboos UniversitySultan Qaboos University Medical Journal2075-051X2075-05282017-10-0117131010.18295/squmj.2016.17.01.0021733Sentinel Lymph Node Biopsy : A new approach in the management of head and neck cancersDeepti Sharma0George Koshy1Sonal Grover2Department of Oral & Maxillofacial Pathology, Christian Dental College & Hospital, Ludhiana, Punjab, IndiaDepartment of Oral & Maxillofacial Pathology, Christian Dental College & Hospital, Ludhiana, Punjab, IndiaDepartment of Oral & Maxillofacial Pathology, Christian Dental College & Hospital, Ludhiana, Punjab, IndiaCervical lymph node metastasis affects the prognosis and overall survival rate of and therapeutic planning for patients with head and neck squamous cell carcinomas (HNSCCs). However, advanced diagnostic modalities still lack accuracy in detecting occult neck metastasis. A sentinel lymph node biopsy is a minimally invasive auxiliary method for assessing the presence of occult metastatic disease in a patient with a clinically negative neck. This technique increases the specificity of neck dissection and thus reduces morbidity among oral cancer patients. The removal of sentinel nodes and dissection of the levels between the primary tumour and the sentinel node or the irradiation of target nodal basins is favoured as a selective treatment approach; this technique has the potential to become the new standard of care for patients with HNSCCs. This article presents an update on clinical applications and novel developments in this field.https://journals.squ.edu.om/index.php/squmj/article/view/1809head and neck cancersquamous cell carcinomasneck dissectionsentinel lymph node biopsylymphoscintigraphy |
| spellingShingle | Deepti Sharma George Koshy Sonal Grover Sentinel Lymph Node Biopsy : A new approach in the management of head and neck cancers Sultan Qaboos University Medical Journal head and neck cancer squamous cell carcinomas neck dissection sentinel lymph node biopsy lymphoscintigraphy |
| title | Sentinel Lymph Node Biopsy : A new approach in the management of head and neck cancers |
| title_full | Sentinel Lymph Node Biopsy : A new approach in the management of head and neck cancers |
| title_fullStr | Sentinel Lymph Node Biopsy : A new approach in the management of head and neck cancers |
| title_full_unstemmed | Sentinel Lymph Node Biopsy : A new approach in the management of head and neck cancers |
| title_short | Sentinel Lymph Node Biopsy : A new approach in the management of head and neck cancers |
| title_sort | sentinel lymph node biopsy a new approach in the management of head and neck cancers |
| topic | head and neck cancer squamous cell carcinomas neck dissection sentinel lymph node biopsy lymphoscintigraphy |
| url | https://journals.squ.edu.om/index.php/squmj/article/view/1809 |
| work_keys_str_mv | AT deeptisharma sentinellymphnodebiopsyanewapproachinthemanagementofheadandneckcancers AT georgekoshy sentinellymphnodebiopsyanewapproachinthemanagementofheadandneckcancers AT sonalgrover sentinellymphnodebiopsyanewapproachinthemanagementofheadandneckcancers |