Abuse of tropicamide eye drops: review of clinical data

Over the past 15 years, the increasing nonmedical use of tropicamide ophthalmic drops has been reported in Europe, coinciding with an increase in opioid addiction and drug-related mortality. Although tropicamide is generally known as a cheap alternative to heroin in Eastern Europe, it still appears...

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Main Authors: Val Bellman, Anastasia Ukolova, Elena Erovichenkova, Sarah Lam, Hirsch K. Srivastava, Jared Bruce, Douglass M. Burgess
Format: Article
Language:English
Published: Associação Brasileira de Psiquiatria (ABP) 2022-06-01
Series:Brazilian Journal of Psychiatry
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462022005006210&tlng=en
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author Val Bellman
Anastasia Ukolova
Elena Erovichenkova
Sarah Lam
Hirsch K. Srivastava
Jared Bruce
Douglass M. Burgess
author_facet Val Bellman
Anastasia Ukolova
Elena Erovichenkova
Sarah Lam
Hirsch K. Srivastava
Jared Bruce
Douglass M. Burgess
author_sort Val Bellman
collection DOAJ
description Over the past 15 years, the increasing nonmedical use of tropicamide ophthalmic drops has been reported in Europe, coinciding with an increase in opioid addiction and drug-related mortality. Although tropicamide is generally known as a cheap alternative to heroin in Eastern Europe, it still appears to be a relatively new phenomenon that has arisen over the last decade. A narrative review was conducted of all the relevant sources published in more than five countries between January 1, 1975 and January 10, 2021. For bibliographic accuracy, the materials published in Russian and Italian were professionally translated to English. During the preparation of this report, we were able to interview five Russian-speaking patients who injected tropicamide in the past and we discuss another case of intravenous tropicamide use. This review was acknowledged by the institutional review board of the University of Missouri-Kansas City. All patients interviewed at the Unica Medical Center consented for their clinical information to be reported in a medical publication. We analyzed data from 50+ various sources and covered a variety of drug-related issues, including information on the extent, patterns, and trends in tropicamide use, its health consequences, and other clinical findings. The information provided in this article may help providers better detect tropicamide abuse and incorporate new rehabilitation strategies into the management of these patients.
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spelling doaj.art-a7fc0c9a2c9d4745bf9462db70e4a54c2022-12-22T03:33:19ZengAssociação Brasileira de Psiquiatria (ABP)Brazilian Journal of Psychiatry1809-452X2022-06-0110.47626/1516-4446-2021-2446Abuse of tropicamide eye drops: review of clinical dataVal Bellmanhttps://orcid.org/0000-0003-0845-2450Anastasia UkolovaElena ErovichenkovaSarah LamHirsch K. SrivastavaJared BruceDouglass M. BurgessOver the past 15 years, the increasing nonmedical use of tropicamide ophthalmic drops has been reported in Europe, coinciding with an increase in opioid addiction and drug-related mortality. Although tropicamide is generally known as a cheap alternative to heroin in Eastern Europe, it still appears to be a relatively new phenomenon that has arisen over the last decade. A narrative review was conducted of all the relevant sources published in more than five countries between January 1, 1975 and January 10, 2021. For bibliographic accuracy, the materials published in Russian and Italian were professionally translated to English. During the preparation of this report, we were able to interview five Russian-speaking patients who injected tropicamide in the past and we discuss another case of intravenous tropicamide use. This review was acknowledged by the institutional review board of the University of Missouri-Kansas City. All patients interviewed at the Unica Medical Center consented for their clinical information to be reported in a medical publication. We analyzed data from 50+ various sources and covered a variety of drug-related issues, including information on the extent, patterns, and trends in tropicamide use, its health consequences, and other clinical findings. The information provided in this article may help providers better detect tropicamide abuse and incorporate new rehabilitation strategies into the management of these patients.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462022005006210&tlng=enTropicamideeye dropsabuseaddictionopiate
spellingShingle Val Bellman
Anastasia Ukolova
Elena Erovichenkova
Sarah Lam
Hirsch K. Srivastava
Jared Bruce
Douglass M. Burgess
Abuse of tropicamide eye drops: review of clinical data
Brazilian Journal of Psychiatry
Tropicamide
eye drops
abuse
addiction
opiate
title Abuse of tropicamide eye drops: review of clinical data
title_full Abuse of tropicamide eye drops: review of clinical data
title_fullStr Abuse of tropicamide eye drops: review of clinical data
title_full_unstemmed Abuse of tropicamide eye drops: review of clinical data
title_short Abuse of tropicamide eye drops: review of clinical data
title_sort abuse of tropicamide eye drops review of clinical data
topic Tropicamide
eye drops
abuse
addiction
opiate
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462022005006210&tlng=en
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AT sarahlam abuseoftropicamideeyedropsreviewofclinicaldata
AT hirschksrivastava abuseoftropicamideeyedropsreviewofclinicaldata
AT jaredbruce abuseoftropicamideeyedropsreviewofclinicaldata
AT douglassmburgess abuseoftropicamideeyedropsreviewofclinicaldata