A Review Study on Macrolides Isolated from Cyanobacteria
Cyanobacteria are rich sources of structurally-diverse molecules with promising pharmacological activities. Marine cyanobacteria have been proven to be true producers of some significant bioactive metabolites from marine invertebrates. Macrolides are a class of bioactive compounds isolated from mari...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-04-01
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| Series: | Marine Drugs |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1660-3397/15/5/126 |
| _version_ | 1828114976541245440 |
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| author | Mengchuan Wang Jinrong Zhang Shan He Xiaojun Yan |
| author_facet | Mengchuan Wang Jinrong Zhang Shan He Xiaojun Yan |
| author_sort | Mengchuan Wang |
| collection | DOAJ |
| description | Cyanobacteria are rich sources of structurally-diverse molecules with promising pharmacological activities. Marine cyanobacteria have been proven to be true producers of some significant bioactive metabolites from marine invertebrates. Macrolides are a class of bioactive compounds isolated from marine organisms, including marine microorganisms in particular. The structural characteristics of macrolides from cyanobacteria mainly manifest in the diversity of carbon skeletons, complexes of chlorinated thiazole-containing molecules and complex spatial configuration. In the present work, we systematically reviewed the structures and pharmacological activities of macrolides from cyanobacteria. Our data would help establish an effective support system for the discovery and development of cyanobacterium-derived macrolides. |
| first_indexed | 2024-04-11T12:33:41Z |
| format | Article |
| id | doaj.art-a7fd2fc627e54590b72286a1a53e80b3 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-04-11T12:33:41Z |
| publishDate | 2017-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-a7fd2fc627e54590b72286a1a53e80b32022-12-22T04:23:41ZengMDPI AGMarine Drugs1660-33972017-04-0115512610.3390/md15050126md15050126A Review Study on Macrolides Isolated from CyanobacteriaMengchuan Wang0Jinrong Zhang1Shan He2Xiaojun Yan3School of Marine Sciences, Laboratory of Marine Natural Products, Ningbo University, Ningbo 315211, ChinaSchool of Marine Sciences, Laboratory of Marine Natural Products, Ningbo University, Ningbo 315211, ChinaSchool of Marine Sciences, Laboratory of Marine Natural Products, Ningbo University, Ningbo 315211, ChinaKey Laboratory of Applied Marine Biotechnology of Ministry of Education, Ningbo University, Ningbo 315211, ChinaCyanobacteria are rich sources of structurally-diverse molecules with promising pharmacological activities. Marine cyanobacteria have been proven to be true producers of some significant bioactive metabolites from marine invertebrates. Macrolides are a class of bioactive compounds isolated from marine organisms, including marine microorganisms in particular. The structural characteristics of macrolides from cyanobacteria mainly manifest in the diversity of carbon skeletons, complexes of chlorinated thiazole-containing molecules and complex spatial configuration. In the present work, we systematically reviewed the structures and pharmacological activities of macrolides from cyanobacteria. Our data would help establish an effective support system for the discovery and development of cyanobacterium-derived macrolides.http://www.mdpi.com/1660-3397/15/5/126cyanobacteriamacrolidessecondary metabolitesbioactivity |
| spellingShingle | Mengchuan Wang Jinrong Zhang Shan He Xiaojun Yan A Review Study on Macrolides Isolated from Cyanobacteria Marine Drugs cyanobacteria macrolides secondary metabolites bioactivity |
| title | A Review Study on Macrolides Isolated from Cyanobacteria |
| title_full | A Review Study on Macrolides Isolated from Cyanobacteria |
| title_fullStr | A Review Study on Macrolides Isolated from Cyanobacteria |
| title_full_unstemmed | A Review Study on Macrolides Isolated from Cyanobacteria |
| title_short | A Review Study on Macrolides Isolated from Cyanobacteria |
| title_sort | review study on macrolides isolated from cyanobacteria |
| topic | cyanobacteria macrolides secondary metabolites bioactivity |
| url | http://www.mdpi.com/1660-3397/15/5/126 |
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