Cardiac MR Imaging in the Evaluation of Rheumatic Valvular Heart Diseases

Introduction: Rheumatic heart disease is the most common cause of valvular heart disease throughout the world. Echocardiography is the dominant imaging investigation in the assessment of cardiac valvular disease and the role of Magnetic Resonance Imaging (MRI) is so far limited. However, due to...

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Main Authors: PHANI CHAKRAVARTY MUTNURU, SN SINGH, JOHN D’ SOUZA, LAKSHMI MANASA PERUBHOTLA
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2016-03-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/7405/18059_CE[Ra1]_F(GH)_PF1(Ro_Om)_PFA(AK)_PF2(PAG).pdf
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author PHANI CHAKRAVARTY MUTNURU
SN SINGH
JOHN D’ SOUZA
LAKSHMI MANASA PERUBHOTLA
author_facet PHANI CHAKRAVARTY MUTNURU
SN SINGH
JOHN D’ SOUZA
LAKSHMI MANASA PERUBHOTLA
author_sort PHANI CHAKRAVARTY MUTNURU
collection DOAJ
description Introduction: Rheumatic heart disease is the most common cause of valvular heart disease throughout the world. Echocardiography is the dominant imaging investigation in the assessment of cardiac valvular disease and the role of Magnetic Resonance Imaging (MRI) is so far limited. However, due to rapid improvements in the cardiac MRI technology in past few years, this non invasive technique is gaining interest in the examination of cardiac valves. Aim: Our study was undertaken to define the role of MRI in the evaluation of Rheumatic valvular heart disease and to compare the role of MRI with transthoracic echocardiography with regard to quantity of stenosis and volume regurgitation. Materials and Methods: ECG gated Cardiac MRI was performed with a 1.5-Tesla system (MAGNETOM SYMPHONYModel 2005) using basic cardiac software (Argus viewer) by a phased-array multicoil on 50 subjects who were known cases of Rheumatic valvular heart disease. A chest radiograph and echocardiography were done in all patients before MR examination. Informed consent was taken from all patients. Results: Mitral stenosis either as an isolated valvular abnormality or in combination with other valvular abnormalities constituted the major bulk of Rheumatic valvular heart disease in our study population. The average ejection fraction by ECHO is 64.94±7.11 and by MRI 67.52±7.84. The average mitral valve area by ECHO is 1.79±0.43 cm2 and by MRI 1.82±0.47 cm2 . The average aortic valve area by ECHO is 1.10±0.21 cm2 and by MRI 1.12±0.25 cm2 . The Coefficient of Correlation (r) is 0.82 for ejection fraction, 0.98 for mitral valve area and 0.92 for aortic valve area which means a strong positive association between the results by ECHO and MRI. In all instances, the p-value is <0.00001, suggesting that the test is highly significant. Conclusion: In our study echocardiography was found to be the gold standard for the diagnosis of Rheumatic valvular heart disease and the role of MRI remained only complimentary to Echocardiography. However with advanced cardiac software, more advanced techniques, and faster imaging sequences, MRI may become a valuable procedure for investigation and followup of patients with valvular heart disease.
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spelling doaj.art-a7fda2f48338479b909f905be8905d582022-12-22T01:00:48ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-03-01103TC06TC0910.7860/JCDR/2016/18059.7405Cardiac MR Imaging in the Evaluation of Rheumatic Valvular Heart DiseasesPHANI CHAKRAVARTY MUTNURU0SN SINGH1JOHN D’ SOUZA2LAKSHMI MANASA PERUBHOTLA3Assistant Professor, Department of Radiology, Nizam’s Institute of Medical Sciences, Punjagutta, Hyderabad, India.Head of Department, Department of Radiology, INHS Kalyani, Visakhapatnam, India.Professor, Department of Radiology, Bharati Vidyapeeth Medical Foundation, Pune, India.Ex Lecturer, Department of Pathology, Nizam’s Institute of Medical Sciences, Punjagutta, Hyderabad, India.Introduction: Rheumatic heart disease is the most common cause of valvular heart disease throughout the world. Echocardiography is the dominant imaging investigation in the assessment of cardiac valvular disease and the role of Magnetic Resonance Imaging (MRI) is so far limited. However, due to rapid improvements in the cardiac MRI technology in past few years, this non invasive technique is gaining interest in the examination of cardiac valves. Aim: Our study was undertaken to define the role of MRI in the evaluation of Rheumatic valvular heart disease and to compare the role of MRI with transthoracic echocardiography with regard to quantity of stenosis and volume regurgitation. Materials and Methods: ECG gated Cardiac MRI was performed with a 1.5-Tesla system (MAGNETOM SYMPHONYModel 2005) using basic cardiac software (Argus viewer) by a phased-array multicoil on 50 subjects who were known cases of Rheumatic valvular heart disease. A chest radiograph and echocardiography were done in all patients before MR examination. Informed consent was taken from all patients. Results: Mitral stenosis either as an isolated valvular abnormality or in combination with other valvular abnormalities constituted the major bulk of Rheumatic valvular heart disease in our study population. The average ejection fraction by ECHO is 64.94±7.11 and by MRI 67.52±7.84. The average mitral valve area by ECHO is 1.79±0.43 cm2 and by MRI 1.82±0.47 cm2 . The average aortic valve area by ECHO is 1.10±0.21 cm2 and by MRI 1.12±0.25 cm2 . The Coefficient of Correlation (r) is 0.82 for ejection fraction, 0.98 for mitral valve area and 0.92 for aortic valve area which means a strong positive association between the results by ECHO and MRI. In all instances, the p-value is <0.00001, suggesting that the test is highly significant. Conclusion: In our study echocardiography was found to be the gold standard for the diagnosis of Rheumatic valvular heart disease and the role of MRI remained only complimentary to Echocardiography. However with advanced cardiac software, more advanced techniques, and faster imaging sequences, MRI may become a valuable procedure for investigation and followup of patients with valvular heart disease.https://jcdr.net/articles/PDF/7405/18059_CE[Ra1]_F(GH)_PF1(Ro_Om)_PFA(AK)_PF2(PAG).pdfnoninvasive imagingstenosisregurgitation
spellingShingle PHANI CHAKRAVARTY MUTNURU
SN SINGH
JOHN D’ SOUZA
LAKSHMI MANASA PERUBHOTLA
Cardiac MR Imaging in the Evaluation of Rheumatic Valvular Heart Diseases
Journal of Clinical and Diagnostic Research
noninvasive imaging
stenosis
regurgitation
title Cardiac MR Imaging in the Evaluation of Rheumatic Valvular Heart Diseases
title_full Cardiac MR Imaging in the Evaluation of Rheumatic Valvular Heart Diseases
title_fullStr Cardiac MR Imaging in the Evaluation of Rheumatic Valvular Heart Diseases
title_full_unstemmed Cardiac MR Imaging in the Evaluation of Rheumatic Valvular Heart Diseases
title_short Cardiac MR Imaging in the Evaluation of Rheumatic Valvular Heart Diseases
title_sort cardiac mr imaging in the evaluation of rheumatic valvular heart diseases
topic noninvasive imaging
stenosis
regurgitation
url https://jcdr.net/articles/PDF/7405/18059_CE[Ra1]_F(GH)_PF1(Ro_Om)_PFA(AK)_PF2(PAG).pdf
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