Prevalence and risk factors for hypokalemia in patients scheduled for laparoscopic colorectal resection and its association with post-operative recovery
Abstract Background Perioperative serum potassium levels are closely associated with postoperative clinical outcomes after gastrointestinal surgery. The aim of our retrospective study was to identify the prevalence and risk factors for preoperative hypokalemia (before pneumoperitoneum) and to evalua...
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| Format: | Article |
| Language: | English |
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BMC
2018-10-01
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| Series: | BMC Gastroenterology |
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| Online Access: | http://link.springer.com/article/10.1186/s12876-018-0876-x |
| _version_ | 1819276555768037376 |
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| author | Qianqian Zhu Xianlong Li Fang Tan Yingqing Deng Chulian Gong Jingping Hu Pinjie Huang Shaoli Zhou |
| author_facet | Qianqian Zhu Xianlong Li Fang Tan Yingqing Deng Chulian Gong Jingping Hu Pinjie Huang Shaoli Zhou |
| author_sort | Qianqian Zhu |
| collection | DOAJ |
| description | Abstract Background Perioperative serum potassium levels are closely associated with postoperative clinical outcomes after gastrointestinal surgery. The aim of our retrospective study was to identify the prevalence and risk factors for preoperative hypokalemia (before pneumoperitoneum) and to evaluate the influence of preoperative hypokalemia on the recovery of postoperative gastrointestinal function. Methods In this retrospective study, patients scheduled for laparoscopic colorectal resection from November 11 2014 to October 20 2016, were considered for inclusion. A blood potassium level between 3.5 and 5.5 mmol/L was defined as normal, with levels between 3.0 to 3.5 mmol/L, 2.5 to 3.0 mmol/L and < 2.5 mmol/L considered as slight, moderate, and severe level of hypokalemia. The factors including age, gender, ASA grade, BMI, hypertension, diabetes, anti-hypertension drugs, lactose oral soluble, oral cathartics, oral cathartics, cathartic enemas, and blood potassium level before gastrointestinal preparation which might be associated with blood potassium level before pneumoperitoneum were analysed. The time to postoperative first flatus (FFL) and first feces (FFE) was compared between patients with and without hypokalemia. Results The final analysis was based on the data of 108 patients. Hypokalemia was identified in 70.37% patients, with the following distribution of blood potassium levels before pneumoperitoneum: slight, 49 (45.37%) patients; moderate, 23 (21.30%); and severe, 4 (3.70%) patients. Hypokalemia was significantly associated with hypertension and the use of ≥2 types of oral cathartics for preoperative gastrointestinal preparation. With treatment, potassium levels recovered to normal levels in all patients within 48 h postoperatively. Hypokalemia was associated with a longer postoperative time to first feces, compared to patients with a normal potassium level before pneumoperitoneum. Conclusions Our findings underlie the importance of early monitoring and management of serum potassium levels in these patients. |
| first_indexed | 2024-12-23T23:42:05Z |
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| id | doaj.art-a7ff1f1e4b68415cb6a4341d4c7b32cc |
| institution | Directory Open Access Journal |
| issn | 1471-230X |
| language | English |
| last_indexed | 2024-12-23T23:42:05Z |
| publishDate | 2018-10-01 |
| publisher | BMC |
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| series | BMC Gastroenterology |
| spelling | doaj.art-a7ff1f1e4b68415cb6a4341d4c7b32cc2022-12-21T17:25:36ZengBMCBMC Gastroenterology1471-230X2018-10-011811610.1186/s12876-018-0876-xPrevalence and risk factors for hypokalemia in patients scheduled for laparoscopic colorectal resection and its association with post-operative recoveryQianqian Zhu0Xianlong Li1Fang Tan2Yingqing Deng3Chulian Gong4Jingping Hu5Pinjie Huang6Shaoli Zhou7Department of Anesthesiology, The Third Affiliated Hospital of Sun Yat-Sen UniversityDepartment of Anesthesiology, The Third Affiliated Hospital of Sun Yat-Sen UniversityDepartment of Anesthesiology, The Seventh Affiliated Hospital of Sun Yat-Sen UniversityDepartment of Anesthesiology, The Third Affiliated Hospital of Sun Yat-Sen UniversityDepartment of Anesthesiology, The Third Affiliated Hospital of Sun Yat-Sen UniversityDepartment of Anesthesiology, The Third Affiliated Hospital of Sun Yat-Sen UniversityDepartment of Anesthesiology, The Third Affiliated Hospital of Sun Yat-Sen UniversityDepartment of Anesthesiology, The Third Affiliated Hospital of Sun Yat-Sen UniversityAbstract Background Perioperative serum potassium levels are closely associated with postoperative clinical outcomes after gastrointestinal surgery. The aim of our retrospective study was to identify the prevalence and risk factors for preoperative hypokalemia (before pneumoperitoneum) and to evaluate the influence of preoperative hypokalemia on the recovery of postoperative gastrointestinal function. Methods In this retrospective study, patients scheduled for laparoscopic colorectal resection from November 11 2014 to October 20 2016, were considered for inclusion. A blood potassium level between 3.5 and 5.5 mmol/L was defined as normal, with levels between 3.0 to 3.5 mmol/L, 2.5 to 3.0 mmol/L and < 2.5 mmol/L considered as slight, moderate, and severe level of hypokalemia. The factors including age, gender, ASA grade, BMI, hypertension, diabetes, anti-hypertension drugs, lactose oral soluble, oral cathartics, oral cathartics, cathartic enemas, and blood potassium level before gastrointestinal preparation which might be associated with blood potassium level before pneumoperitoneum were analysed. The time to postoperative first flatus (FFL) and first feces (FFE) was compared between patients with and without hypokalemia. Results The final analysis was based on the data of 108 patients. Hypokalemia was identified in 70.37% patients, with the following distribution of blood potassium levels before pneumoperitoneum: slight, 49 (45.37%) patients; moderate, 23 (21.30%); and severe, 4 (3.70%) patients. Hypokalemia was significantly associated with hypertension and the use of ≥2 types of oral cathartics for preoperative gastrointestinal preparation. With treatment, potassium levels recovered to normal levels in all patients within 48 h postoperatively. Hypokalemia was associated with a longer postoperative time to first feces, compared to patients with a normal potassium level before pneumoperitoneum. Conclusions Our findings underlie the importance of early monitoring and management of serum potassium levels in these patients.http://link.springer.com/article/10.1186/s12876-018-0876-xHypokalemiaGastrointestinal preparationRisk factors |
| spellingShingle | Qianqian Zhu Xianlong Li Fang Tan Yingqing Deng Chulian Gong Jingping Hu Pinjie Huang Shaoli Zhou Prevalence and risk factors for hypokalemia in patients scheduled for laparoscopic colorectal resection and its association with post-operative recovery BMC Gastroenterology Hypokalemia Gastrointestinal preparation Risk factors |
| title | Prevalence and risk factors for hypokalemia in patients scheduled for laparoscopic colorectal resection and its association with post-operative recovery |
| title_full | Prevalence and risk factors for hypokalemia in patients scheduled for laparoscopic colorectal resection and its association with post-operative recovery |
| title_fullStr | Prevalence and risk factors for hypokalemia in patients scheduled for laparoscopic colorectal resection and its association with post-operative recovery |
| title_full_unstemmed | Prevalence and risk factors for hypokalemia in patients scheduled for laparoscopic colorectal resection and its association with post-operative recovery |
| title_short | Prevalence and risk factors for hypokalemia in patients scheduled for laparoscopic colorectal resection and its association with post-operative recovery |
| title_sort | prevalence and risk factors for hypokalemia in patients scheduled for laparoscopic colorectal resection and its association with post operative recovery |
| topic | Hypokalemia Gastrointestinal preparation Risk factors |
| url | http://link.springer.com/article/10.1186/s12876-018-0876-x |
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