Kallistatin inhibits tumour progression and platinum resistance in high-grade serous ovarian cancer

Kallistatin inhibits tumour progression and platinum resistance in high-grade serous ovarian cancer

Abstract Ovarian cancer is the most lethal gynaecologic malignancy. Although there are various subtypes of ovarian cancer, high-grade serous ovarian cancer (HGSOC) accounts for 70% of ovarian cancer deaths. Chemoresistance is the primary reason for the unfavourable prognosis of HGSOC. Kallistatin (K...

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Bibliographic Details
Main Authors: Huan Wu, Rongrong Li, Zhiwei Zhang, Huiyang Jiang, Hanlin Ma, Cunzhong Yuan, Chenggong Sun, Yingwei Li, Beihua Kong
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Journal of Ovarian Research
Subjects:
Kallistatin
High-grade serous ovarian cancer
Proliferation
Metastasis
Platinum resistance
Apoptosis
Online Access:https://doi.org/10.1186/s13048-019-0601-6

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