Vancomycin efficiency and safety of a dosage of 40–60 mg/kg/d and corresponding trough concentrations in children with Gram-positive bacterial sepsis

Vancomycin efficiency and safety of a dosage of 40–60 mg/kg/d and corresponding trough concentrations in children with Gram-positive bacterial sepsis

BackgroundOptimal vancomycin trough concentrations and dosages remain controversial in sepsis children. We aim to investigate vancomycin treatment outcomes with a dosage of 40-60 mg/kg/d and corresponding trough concentrations in children with Gram-positive bacterial sepsis from a clinical perspecti...

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Bibliographic Details
Main Authors: Lengyue Peng, Ziyao Guo, Guangli Zhang, Xiaoyin Tian, Ruixue Gu, Qinyuan Li, Yuanyuan Li, Zhengxiu Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
vancomycin
Gram-positive bacterial
children
tough concentrations
dosages
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1117717/full

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