Extraction of Glycyrrhizic Acid from Glycyrrhiza uralensis Using Ultrasound and Its Process Extraction Model
This work focused on the intensification of extraction process of glycyrrhizic acid (GA) from Glycyrrhiza uralensis using ultrasound-assisted extraction (UAE) method. Various process parameters such as ultrasonic power, ultrasonic frequency, extraction temperature, and extraction time which affect t...
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| Format: | Article |
| Language: | English |
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MDPI AG
2016-10-01
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| Series: | Applied Sciences |
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| Online Access: | http://www.mdpi.com/2076-3417/6/11/319 |
| _version_ | 1819013688974114816 |
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| author | Jiangqing Liao Baida Qu Nan Zheng |
| author_facet | Jiangqing Liao Baida Qu Nan Zheng |
| author_sort | Jiangqing Liao |
| collection | DOAJ |
| description | This work focused on the intensification of extraction process of glycyrrhizic acid (GA) from Glycyrrhiza uralensis using ultrasound-assisted extraction (UAE) method. Various process parameters such as ultrasonic power, ultrasonic frequency, extraction temperature, and extraction time which affect the extraction yield were optimized. The results showed that all process parameters had exhibited significant influences on the GA extraction. The highest GA yield of 217.7 mg/g was obtained at optimized parameters of 125 W, 55 kHz, 25 °C, and 10 min. Furthermore, the extraction kinetics model of this process was also investigated based on Fick’s first law available in the literature. Kinetic parameters such as equilibrium concentration (Ce) and integrated influence coefficient (λ) for different ultrasonic powers, ultrasonic frequencies, and extraction temperatures were predicted. Model validations were done successfully with the average of relative deviation between 0.96% and 4.36% by plotting experimental and predicted values of concentration of GA in extract. This indicated that the developed extraction model could reflect the effectiveness of the extraction of GA from Glycyrrhiza uralensis and therefore serve as the guide for comprehending other UAE process. |
| first_indexed | 2024-12-21T02:03:56Z |
| format | Article |
| id | doaj.art-a80325849a6c4210a46031eeef3209c1 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-12-21T02:03:56Z |
| publishDate | 2016-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-a80325849a6c4210a46031eeef3209c12022-12-21T19:19:33ZengMDPI AGApplied Sciences2076-34172016-10-0161131910.3390/app6110319app6110319Extraction of Glycyrrhizic Acid from Glycyrrhiza uralensis Using Ultrasound and Its Process Extraction ModelJiangqing Liao0Baida Qu1Nan Zheng2Key Laboratory of Industrial Advanced Process Control for Light Industry of Ministry of Education, Jiangnan University, Wuxi 214122, ChinaKey Laboratory of Industrial Advanced Process Control for Light Industry of Ministry of Education, Jiangnan University, Wuxi 214122, ChinaSchool of Chemical and Environment Science, Shaanxi University of Technology, Hanzhong 723001, ChinaThis work focused on the intensification of extraction process of glycyrrhizic acid (GA) from Glycyrrhiza uralensis using ultrasound-assisted extraction (UAE) method. Various process parameters such as ultrasonic power, ultrasonic frequency, extraction temperature, and extraction time which affect the extraction yield were optimized. The results showed that all process parameters had exhibited significant influences on the GA extraction. The highest GA yield of 217.7 mg/g was obtained at optimized parameters of 125 W, 55 kHz, 25 °C, and 10 min. Furthermore, the extraction kinetics model of this process was also investigated based on Fick’s first law available in the literature. Kinetic parameters such as equilibrium concentration (Ce) and integrated influence coefficient (λ) for different ultrasonic powers, ultrasonic frequencies, and extraction temperatures were predicted. Model validations were done successfully with the average of relative deviation between 0.96% and 4.36% by plotting experimental and predicted values of concentration of GA in extract. This indicated that the developed extraction model could reflect the effectiveness of the extraction of GA from Glycyrrhiza uralensis and therefore serve as the guide for comprehending other UAE process.http://www.mdpi.com/2076-3417/6/11/319ultrasoundextractionglycyrrhizic acidGlycyrrhiza uralensismodel |
| spellingShingle | Jiangqing Liao Baida Qu Nan Zheng Extraction of Glycyrrhizic Acid from Glycyrrhiza uralensis Using Ultrasound and Its Process Extraction Model Applied Sciences ultrasound extraction glycyrrhizic acid Glycyrrhiza uralensis model |
| title | Extraction of Glycyrrhizic Acid from Glycyrrhiza uralensis Using Ultrasound and Its Process Extraction Model |
| title_full | Extraction of Glycyrrhizic Acid from Glycyrrhiza uralensis Using Ultrasound and Its Process Extraction Model |
| title_fullStr | Extraction of Glycyrrhizic Acid from Glycyrrhiza uralensis Using Ultrasound and Its Process Extraction Model |
| title_full_unstemmed | Extraction of Glycyrrhizic Acid from Glycyrrhiza uralensis Using Ultrasound and Its Process Extraction Model |
| title_short | Extraction of Glycyrrhizic Acid from Glycyrrhiza uralensis Using Ultrasound and Its Process Extraction Model |
| title_sort | extraction of glycyrrhizic acid from glycyrrhiza uralensis using ultrasound and its process extraction model |
| topic | ultrasound extraction glycyrrhizic acid Glycyrrhiza uralensis model |
| url | http://www.mdpi.com/2076-3417/6/11/319 |
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