In Depth Natural Product Discovery from the Basidiomycetes <i>Stereum</i> Species
Natural metabolites from microorganisms play significant roles in the discovery of drugs, both for disease treatments in humans, and applications in agriculture. The Basidiomycetes <i>Stereum</i> genus has been a source of such bioactive compounds. Here we report on the structures and ac...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-07-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/8/7/1049 |
| _version_ | 1827713059929456640 |
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| author | Mengqing Tian Peiji Zhao Guohong Li Keqin Zhang |
| author_facet | Mengqing Tian Peiji Zhao Guohong Li Keqin Zhang |
| author_sort | Mengqing Tian |
| collection | DOAJ |
| description | Natural metabolites from microorganisms play significant roles in the discovery of drugs, both for disease treatments in humans, and applications in agriculture. The Basidiomycetes <i>Stereum</i> genus has been a source of such bioactive compounds. Here we report on the structures and activities of secondary metabolites from <i>Stereum</i>. Their structural types include sesquiterpenoids, polyketides, vibralactones, triterpenoids, sterols, carboxylic acids and saccharides. Most of them showed biological activities including cytotoxic, antibacterial, antifungal, antiviral, radical scavenging activity, autophagy inducing activity, inhibiting pancreatic lipase against malarial parasite, nematocidal and so on. The syntheses of some metabolites have been studied. In this review, 238 secondary metabolites from 10 known species and various unidentified species of <i>Stereum</i> were summarized over the last seven decades. |
| first_indexed | 2024-03-10T18:27:52Z |
| format | Article |
| id | doaj.art-a8049dfe81a948b2ba4b906c21b67856 |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-10T18:27:52Z |
| publishDate | 2020-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-a8049dfe81a948b2ba4b906c21b678562023-11-20T06:50:45ZengMDPI AGMicroorganisms2076-26072020-07-0187104910.3390/microorganisms8071049In Depth Natural Product Discovery from the Basidiomycetes <i>Stereum</i> SpeciesMengqing Tian0Peiji Zhao1Guohong Li2Keqin Zhang3State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, and Key Laboratory for Southwest Microbial Diversity of the Ministry of Education, Yunnan University, Kunming 650032, ChinaState Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, and Key Laboratory for Southwest Microbial Diversity of the Ministry of Education, Yunnan University, Kunming 650032, ChinaState Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, and Key Laboratory for Southwest Microbial Diversity of the Ministry of Education, Yunnan University, Kunming 650032, ChinaState Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, and Key Laboratory for Southwest Microbial Diversity of the Ministry of Education, Yunnan University, Kunming 650032, ChinaNatural metabolites from microorganisms play significant roles in the discovery of drugs, both for disease treatments in humans, and applications in agriculture. The Basidiomycetes <i>Stereum</i> genus has been a source of such bioactive compounds. Here we report on the structures and activities of secondary metabolites from <i>Stereum</i>. Their structural types include sesquiterpenoids, polyketides, vibralactones, triterpenoids, sterols, carboxylic acids and saccharides. Most of them showed biological activities including cytotoxic, antibacterial, antifungal, antiviral, radical scavenging activity, autophagy inducing activity, inhibiting pancreatic lipase against malarial parasite, nematocidal and so on. The syntheses of some metabolites have been studied. In this review, 238 secondary metabolites from 10 known species and various unidentified species of <i>Stereum</i> were summarized over the last seven decades.https://www.mdpi.com/2076-2607/8/7/1049Basidiomycetes<i>Stereum</i>metabolitesbioactivity |
| spellingShingle | Mengqing Tian Peiji Zhao Guohong Li Keqin Zhang In Depth Natural Product Discovery from the Basidiomycetes <i>Stereum</i> Species Microorganisms Basidiomycetes <i>Stereum</i> metabolites bioactivity |
| title | In Depth Natural Product Discovery from the Basidiomycetes <i>Stereum</i> Species |
| title_full | In Depth Natural Product Discovery from the Basidiomycetes <i>Stereum</i> Species |
| title_fullStr | In Depth Natural Product Discovery from the Basidiomycetes <i>Stereum</i> Species |
| title_full_unstemmed | In Depth Natural Product Discovery from the Basidiomycetes <i>Stereum</i> Species |
| title_short | In Depth Natural Product Discovery from the Basidiomycetes <i>Stereum</i> Species |
| title_sort | in depth natural product discovery from the basidiomycetes i stereum i species |
| topic | Basidiomycetes <i>Stereum</i> metabolites bioactivity |
| url | https://www.mdpi.com/2076-2607/8/7/1049 |
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