Genome-wide profiling of histone h3 lysine 4 and lysine 27 trimethylation reveals an epigenetic signature in prostate carcinogenesis.

Genome-wide profiling of histone h3 lysine 4 and lysine 27 trimethylation reveals an epigenetic signature in prostate carcinogenesis.

<h4>Background</h4>Increasing evidence implicates the critical roles of epigenetic regulation in cancer. Very recent reports indicate that global gene silencing in cancer is associated with specific epigenetic modifications. However, the relationship between epigenetic switches and more...

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Main Authors: Xi-Song Ke, Yi Qu, Kari Rostad, Wen-Cheng Li, Biaoyang Lin, Ole Johan Halvorsen, Svein A Haukaas, Inge Jonassen, Kjell Petersen, Naomi Goldfinger, Varda Rotter, Lars A Akslen, Anne M Oyan, Karl-Henning Kalland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19262738/?tool=EBI

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