mRNA vaccines induce rapid antibody responses in mice

mRNA vaccines induce rapid antibody responses in mice

Abstract mRNA vaccines can be developed and produced quickly, making them prime candidates for immediate outbreak responses. Furthermore, clinical trials have demonstrated rapid protection following mRNA vaccination. Thus, we sought to investigate how quickly mRNA vaccines elicit antibody responses...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Makda S. Gebre, Susanne Rauch, Nicole Roth, Janina Gergen, Jingyou Yu, Xiaowen Liu, Andrew C. Cole, Stefan O. Mueller, Benjamin Petsch, Dan H. Barouch
Natura:	Articolo
Lingua:	English
Pubblicazione:	Nature Portfolio 2022-08-01
Serie:	npj Vaccines
Accesso online:	https://doi.org/10.1038/s41541-022-00511-y

Documenti analoghi

mRNA-based SARS-CoV-2 vaccine candidate CVnCoV induces high levels of virus-neutralising antibodies and mediates protection in rodents
di: Susanne Rauch, et al.
Pubblicazione: (2021-04-01)

Optimised Non-Coding Regions of mRNA SARS-CoV-2 Vaccine CV2CoV Improves Homologous and Heterologous Neutralising Antibody Responses
di: Nicole Roth, et al.
Pubblicazione: (2022-08-01)

mRNA vaccine-induced IgG mediates nasal SARS-CoV-2 clearance in mice
di: Charlie Fricke, et al.
Pubblicazione: (2024-12-01)

Assessment of Immunogenicity and Efficacy of CV0501 mRNA-Based Omicron COVID-19 Vaccination in Small Animal Models
di: Nicole Roth, et al.
Pubblicazione: (2023-01-01)

Efficacy of an unmodified bivalent mRNA vaccine against SARS-CoV-2 variants in female small animal models
di: Björn Corleis, et al.
Pubblicazione: (2023-02-01)

mRNA Vaccine Protects against Zika Virus
di: Lex G. Medina-Magües, et al.
Pubblicazione: (2021-12-01)

Durability and expansion of neutralizing antibody breadth following Ad26.COV2.S vaccination of mice
di: Shant H. Mahrokhian, et al.
Pubblicazione: (2022-02-01)

mRNA-based VP8* nanoparticle vaccines against rotavirus are highly immunogenic in rodents
di: Sandro Roier, et al.
Pubblicazione: (2023-12-01)

A third dose of the unmodified COVID-19 mRNA vaccine CVnCoV enhances quality and quantity of immune responses
di: Klara Lenart, et al.
Pubblicazione: (2022-12-01)

Immunogenicity and protective activity of mRNA vaccine candidates against yellow fever virus in animal models
di: Lex G. Medina-Magües, et al.
Pubblicazione: (2023-03-01)

Rapid development of double-hit mRNA antibody cocktail against orthopoxviruses
di: Hang Chi, et al.
Pubblicazione: (2024-03-01)

mRNA booster vaccination protects aged mice against the SARS-CoV-2 Omicron variant
di: Etsuro Nanishi, et al.
Pubblicazione: (2022-08-01)

Comparative immunogenicity of an mRNA/LNP and a DNA vaccine targeting HIV gag conserved elements in macaques
di: Antonio Valentin, et al.
Pubblicazione: (2022-07-01)

CRISPR–Cas9 Genetic Analysis of Virus–Host Interactions
di: Makda Gebre, et al.
Pubblicazione: (2018-01-01)

MSD-based assays facilitate a rapid and quantitative serostatus profiling for the presence of anti-AAV antibodies
di: Janina Haar, et al.
Pubblicazione: (2022-06-01)

Rapid identification of neutralizing antibodies against SARS-CoV-2 variants by mRNA display
di: Shiho Tanaka, et al.
Pubblicazione: (2022-02-01)

Preclinical characterization of an mRNA-encoded anti-Claudin 18.2 antibody
di: Hayat Bähr-Mahmud, et al.
Pubblicazione: (2023-12-01)

Rapid, robust, and sustainable antibody responses to mRNA COVID-19 vaccine in convalescent COVID-19 individuals
di: Sabrina E. Racine-Brzostek, et al.
Pubblicazione: (2021-10-01)

Unmodified rabies mRNA vaccine elicits high cross-neutralizing antibody titers and diverse B cell memory responses
di: Fredrika Hellgren, et al.
Pubblicazione: (2023-06-01)

Advances in RNA Vaccines for Preventive Indications: A Case Study of a Vaccine against Rabies
di: Nicole Armbruster, et al.
Pubblicazione: (2019-09-01)

mRNA-Based Vaccines Are Highly Immunogenic and Confer Protection in the Gnotobiotic Pig Model of Human Rotavirus Diarrhea
di: Casey Hensley, et al.
Pubblicazione: (2024-03-01)

RETRACTED: Heterogeneous Longitudinal Antibody Responses to Covid-19 mRNA Vaccination
di: Suzanne M de la Monte, et al.
Pubblicazione: (2021-10-01)

Advancements in mRNA Encoded Antibodies for Passive Immunotherapy
di: Cailin E. Deal, et al.
Pubblicazione: (2021-01-01)

Engineered mRNA and the Rise of Next-Generation Antibodies
di: Laura Sanz, et al.
Pubblicazione: (2021-09-01)

Author Correction: Unmodified rabies mRNA vaccine elicits high cross-neutralizing antibody titers and diverse B cell memory responses
di: Fredrika Hellgren, et al.
Pubblicazione: (2023-07-01)

The Screening of Broadly Neutralizing Antibodies Targeting the SARS-CoV-2 Spike Protein by mRNA Immunization in Mice
di: Zhiyin An, et al.
Pubblicazione: (2023-05-01)

PP 8.1 – 00003 Optimization of the 5′ cap and untranslated regions enhances the immunogenicity of an mRNA-based therapeutic vaccine in SIV-infected rhesus macaques on ART
di: W. Omange, et al.
Pubblicazione: (2022-12-01)

How mRNA therapeutics are entering the monoclonal antibody field
di: Lien Van Hoecke, et al.
Pubblicazione: (2019-02-01)

mRNA Encoding a Bispecific Single Domain Antibody Construct Protects against Influenza A Virus Infection in Mice
di: Lien Van Hoecke, et al.
Pubblicazione: (2020-06-01)

mRNA vaccines expressing malaria transmission-blocking antigens Pfs25 and Pfs230D1 induce a functional immune response
di: Puthupparampil V. Scaria, et al.
Pubblicazione: (2024-01-01)

Early Emerging SARS-CoV-2 Spike Mutants Are Diversified in Virologic Properties but Elicit Compromised Antibody Responses
di: Junhao Fan, et al.
Pubblicazione: (2023-12-01)

Rapid Field Immunoassay for Detecting Antibody to Sin Nombre Virus in Deer Mice
di: Tony Schountz, et al.
Pubblicazione: (2007-10-01)

Intraduodenal Delivery of Exosome-Loaded SARS-CoV-2 RBD mRNA Induces a Neutralizing Antibody Response in Mice
di: Quan Zhang, et al.
Pubblicazione: (2023-03-01)

Ekspresi mRNA calprotectin neutrofil penderita rapidly progressive periodontitis
di: , UTAMI, Trianna Wahyu, et al.
Pubblicazione: (2008)

mRNA secondary structures fold sequentially but exchange rapidly in vivo.
di: Elisabeth M Mahen, et al.
Pubblicazione: (2010-02-01)

Profiling antibody epitopes induced by mRNA-1273 vaccination and boosters
di: Bethany Girard, et al.
Pubblicazione: (2024-03-01)

Immunogenicity of Low-Dose Prime-Boost Vaccination of mRNA Vaccine CV07050101 in Non-Human Primates
di: Neeltje van Doremalen, et al.
Pubblicazione: (2021-08-01)

Phenylalanine hydroxylase mRNA rescues the phenylketonuria phenotype in mice
di: Maximiliano L. Cacicedo, et al.
Pubblicazione: (2022-10-01)

Toxic Epidermal Necrolysis after COVID-19 mRNA-1237 Vaccination
di: Nicole Hehr, et al.
Pubblicazione: (2023-01-01)

Rapid identification of A29L antibodies based on mRNA immunization and high-throughput single B cell sequencing to detect Monkeypox virus
di: Huisheng Sun, et al.
Pubblicazione: (2024-12-01)