Influence of Varying Pre-Culture Conditions on the Level of Population Heterogeneity in Batch Cultures with an <i>Escherichia coli</i> Triple Reporter Strain

Influence of Varying Pre-Culture Conditions on the Level of Population Heterogeneity in Batch Cultures with an <i>Escherichia coli</i> Triple Reporter Strain

When targeting robust, high-yielding bioprocesses, phenomena such as population heterogeneity have to be considered. Therefore, the influence of the conditions which the cells experience prior to the main culture should also be evaluated. Here, the influence of a pre-culture medium (complex vs. mini...

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Bibliographic Details
Main Authors: Manh Dat Hoang, Sophi Riessner, Jose Enrique Oropeza Vargas, Nikolas von den Eichen, Anna-Lena Heins
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Microorganisms
Subjects:
pre-culture
population heterogeneity
triple reporter strain
batch culture
principal component analysis
Online Access:https://www.mdpi.com/2076-2607/11/7/1763

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