Adherent vs. Free-Floating Neural Induction by Dual SMAD Inhibition for Neurosphere Cultures Derived from Human Induced Pluripotent Stem Cells

Adherent vs. Free-Floating Neural Induction by Dual SMAD Inhibition for Neurosphere Cultures Derived from Human Induced Pluripotent Stem Cells

Keeping neural stem cells under proliferation, followed by terminal differentiation, can substantially increase the number of neurons generated. With regard to the usability of proliferating neurospheres (NSPHs) cultures, adherent induction protocols have not yet been studied in comparison to embryo...

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Bibliographic Details
Main Authors:	Martje G. Pauly, Victor Krajka, Felix Stengel, Philip Seibler, Christine Klein, Philipp Capetian
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-02-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	neural stem cell culture induced pluripotent stem cells neural induction adherent neural induction embryoid bodies neural differentiation
Online Access:	http://journal.frontiersin.org/article/10.3389/fcell.2018.00003/full

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