Synthesis of CuxO/Ag nanoparticles on exfoliated graphene: application for enhanced electrochemical detection of H2O2 in milk
Abstract In this paper, a novel composite is constructed as a non-enzymatic hydrogen peroxide (H2O2) sensor by liquid-phase exfoliation method, which is composed of copper oxide, cuprous oxide and silver nanoparticles doped few-layer-graphene (CuxO/Ag@FLG). Its surface morphology and composition wer...
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| Format: | Article |
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Nature Portfolio
2023-04-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-33661-7 |
| _version_ | 1797836498076172288 |
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| author | Jie Song Yating Wan Chen Yang Qiuju Deng Yingde Cui Zhihong Yan Yi Liu |
| author_facet | Jie Song Yating Wan Chen Yang Qiuju Deng Yingde Cui Zhihong Yan Yi Liu |
| author_sort | Jie Song |
| collection | DOAJ |
| description | Abstract In this paper, a novel composite is constructed as a non-enzymatic hydrogen peroxide (H2O2) sensor by liquid-phase exfoliation method, which is composed of copper oxide, cuprous oxide and silver nanoparticles doped few-layer-graphene (CuxO/Ag@FLG). Its surface morphology and composition were characterized by scanning electron microscopy (SEM) and X-ray photo spectroscopy (XPS), and its H2O2 sensing performances include catalytic reduction and quantitative detection were studied with electrochemical methods. Our sensor had a high sensitivity of 174.5 μA mM−1 cm−2 (R2 = 0.9978) in an extremely wide range of concentrations from 10 μM to 100 mM, a fast response (about 5 s) and a low limit of detection (S/N = 3) of 2.13 μM. The sensor exhibits outstanding selectivity in the presence of various biological interference, such as dopamine, ascorbic acid, uric acid, citric acid, etc. In addition, the constructed sensor continued 95% current responsiveness after 1 month of storage further points to its long-term stability. Last but not least, it has a good recovery rate (90.12–102.00%) in milk sold on the open market, indicating that it has broad application possibilities in the food industry and biological medicine. |
| first_indexed | 2024-04-09T15:10:55Z |
| format | Article |
| id | doaj.art-a80c15cd89e444c29ee805eb8bdaa70f |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-09T15:10:55Z |
| publishDate | 2023-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-a80c15cd89e444c29ee805eb8bdaa70f2023-04-30T11:13:01ZengNature PortfolioScientific Reports2045-23222023-04-0113111210.1038/s41598-023-33661-7Synthesis of CuxO/Ag nanoparticles on exfoliated graphene: application for enhanced electrochemical detection of H2O2 in milkJie Song0Yating Wan1Chen Yang2Qiuju Deng3Yingde Cui4Zhihong Yan5Yi Liu6School of Pharmaceutical and Chemical Engineering, Guangdong Pharmaceutical UniversitySchool of Pharmaceutical and Chemical Engineering, Guangdong Pharmaceutical UniversitySchool of Pharmaceutical and Chemical Engineering, Guangdong Pharmaceutical UniversitySchool of Pharmaceutical and Chemical Engineering, Guangdong Pharmaceutical UniversityGuangzhou Vocational University of Science and TechnologyCollege of Pharmacy, Guangdong Pharmaceutical UniversitySchool of Pharmaceutical and Chemical Engineering, Guangdong Pharmaceutical UniversityAbstract In this paper, a novel composite is constructed as a non-enzymatic hydrogen peroxide (H2O2) sensor by liquid-phase exfoliation method, which is composed of copper oxide, cuprous oxide and silver nanoparticles doped few-layer-graphene (CuxO/Ag@FLG). Its surface morphology and composition were characterized by scanning electron microscopy (SEM) and X-ray photo spectroscopy (XPS), and its H2O2 sensing performances include catalytic reduction and quantitative detection were studied with electrochemical methods. Our sensor had a high sensitivity of 174.5 μA mM−1 cm−2 (R2 = 0.9978) in an extremely wide range of concentrations from 10 μM to 100 mM, a fast response (about 5 s) and a low limit of detection (S/N = 3) of 2.13 μM. The sensor exhibits outstanding selectivity in the presence of various biological interference, such as dopamine, ascorbic acid, uric acid, citric acid, etc. In addition, the constructed sensor continued 95% current responsiveness after 1 month of storage further points to its long-term stability. Last but not least, it has a good recovery rate (90.12–102.00%) in milk sold on the open market, indicating that it has broad application possibilities in the food industry and biological medicine.https://doi.org/10.1038/s41598-023-33661-7 |
| spellingShingle | Jie Song Yating Wan Chen Yang Qiuju Deng Yingde Cui Zhihong Yan Yi Liu Synthesis of CuxO/Ag nanoparticles on exfoliated graphene: application for enhanced electrochemical detection of H2O2 in milk Scientific Reports |
| title | Synthesis of CuxO/Ag nanoparticles on exfoliated graphene: application for enhanced electrochemical detection of H2O2 in milk |
| title_full | Synthesis of CuxO/Ag nanoparticles on exfoliated graphene: application for enhanced electrochemical detection of H2O2 in milk |
| title_fullStr | Synthesis of CuxO/Ag nanoparticles on exfoliated graphene: application for enhanced electrochemical detection of H2O2 in milk |
| title_full_unstemmed | Synthesis of CuxO/Ag nanoparticles on exfoliated graphene: application for enhanced electrochemical detection of H2O2 in milk |
| title_short | Synthesis of CuxO/Ag nanoparticles on exfoliated graphene: application for enhanced electrochemical detection of H2O2 in milk |
| title_sort | synthesis of cuxo ag nanoparticles on exfoliated graphene application for enhanced electrochemical detection of h2o2 in milk |
| url | https://doi.org/10.1038/s41598-023-33661-7 |
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