Receptor tyrosine kinases modulate distinct transcriptional programs by differential usage of intracellular pathways

Receptor tyrosine kinases modulate distinct transcriptional programs by differential usage of intracellular pathways

Receptor tyrosine kinases (RTKs) signal through shared intracellular pathways yet mediate distinct outcomes across many cell types. To investigate the mechanisms underlying RTK specificity in craniofacial development, we performed RNA-seq to delineate the transcriptional response to platelet-derived...

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Bibliographic Details
Main Authors: Harish N Vasudevan, Pierre Mazot, Fenglei He, Philippe Soriano
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-05-01
Series:eLife
Subjects:
RTK
PDGF
FGF
transcription
craniofacial development
Online Access:https://elifesciences.org/articles/07186

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