Receptor tyrosine kinases modulate distinct transcriptional programs by differential usage of intracellular pathways

Receptor tyrosine kinases modulate distinct transcriptional programs by differential usage of intracellular pathways

Receptor tyrosine kinases (RTKs) signal through shared intracellular pathways yet mediate distinct outcomes across many cell types. To investigate the mechanisms underlying RTK specificity in craniofacial development, we performed RNA-seq to delineate the transcriptional response to platelet-derived...

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Detalles Bibliográficos
Main Authors: Harish N Vasudevan, Pierre Mazot, Fenglei He, Philippe Soriano
Formato: Artigo
Idioma:English
Publicado: eLife Sciences Publications Ltd 2015-05-01
Series:eLife
Subjects:
RTK
PDGF
FGF
transcription
craniofacial development
Acceso en liña:https://elifesciences.org/articles/07186

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