Effect of 3-arylamino-1,2-dihydro-3H-1,4-benzodiazepine-2-ones on the bradykinin-induced smooth muscle contraction

Effect of 3-arylamino-1,2-dihydro-3H-1,4-benzodiazepine-2-ones on the bradykinin-induced smooth muscle contraction

Damage to tissue, inflammation and disruption of normal functioning of organs are often accompanied by pain. In pain perceptions, the kinin-kallikrein system with bradykinin as mediator is very important. Regulatory activity of the kinin-kallikrein system permits the control of inflammation, pain, v...

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Bibliographic Details
Main Authors: P. A. Virych, O. V. Shelyuk, T. A. Kabanova, O. I. Khalimova, V. S. Martynyuk, V. I. Pavlovsky, S. A. Andronati
Format: Article
Language:English
Published: Oles Honchar Dnipro National University 2017-01-01
Series:Regulatory Mechanisms in Biosystems
Subjects:
3-substituted 1,4-benzodiazepines
bradykinin
kinin-kallikrein system
maximal normalized rate
Online Access:https://medicine.dp.ua/index.php/med/article/view/300

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