Blood CD3-(CD56 or 16)+ natural killer cell distributions are heterogeneous in healthy adults and suppressed by azathioprine in patients with ANCA-associated vasculitides

Blood CD3-(CD56 or 16)+ natural killer cell distributions are heterogeneous in healthy adults and suppressed by azathioprine in patients with ANCA-associated vasculitides

Abstract Background Cytotoxic Natural Killer (NK) cells are increasingly recognized as a powerful tool to induce targeted cell death in cancer and autoimmune diseases. Still, basic blood NK cell parameters are poorly defined. The aims of this study were 1) to establish reference values of NK cell co...

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Bibliographic Details
Main Authors: Wolfgang Merkt, Ulrich Salzer, Jens Thiel, Ilona Jandova, Raoul Bergner, Ana C. Venhoff, Nils Venhoff
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Immunology
Subjects:
ANCA-associated vasculitis
Natural killer cells
Azathioprine
Online Access:https://doi.org/10.1186/s12865-021-00416-w

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