Borneol facilitates the whitening and anti-wrinkle effect of the essential oil extracted from Abies koreana needles
It has been reported that the essential oil extracted from Abies koreana has skin-improving activity, such as anti-wrinkle and whitening effect. However, the key ingredients that facilitate such biological activity has not been fully elucidated. In the present study, to identify the key skin-improvi...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-11-01
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| Series: | Journal of King Saud University: Science |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1018364723003488 |
| _version_ | 1797653972642693120 |
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| author | Il-Kwon Kim Bomi Kim Byeong-Wook Song Sang Woo Kim Dongsoo Kim Jung Hwa Kang Sung Hwan Hwang Ki-Chul Hwang Seahyoung Lee |
| author_facet | Il-Kwon Kim Bomi Kim Byeong-Wook Song Sang Woo Kim Dongsoo Kim Jung Hwa Kang Sung Hwan Hwang Ki-Chul Hwang Seahyoung Lee |
| author_sort | Il-Kwon Kim |
| collection | DOAJ |
| description | It has been reported that the essential oil extracted from Abies koreana has skin-improving activity, such as anti-wrinkle and whitening effect. However, the key ingredients that facilitate such biological activity has not been fully elucidated. In the present study, to identify the key skin-improving component(s) of the A. koreana essential oil, 10 sequentially fractioned essential oil from A. koreana pine by hydrodistillation were examined for their effect on tyrosinase activity. Out of 10 fractions, only 1 fraction significantly suppressed tyrosinase activity, and subsequent GC/MS analysis indicated that borneol and its acetate ester, bornyl acetate, were unique to the effective fraction, suggesting they are responsible for the skin-improving activity of the essential oil from A. koreana. The biological activity of borneol was evaluated, and borneol significantly inhibited ultraviolet irradiation-induced tyrosinase and matrix metalloproteinase 1 activity while maintain collagen type I synthesis. The results of this study suggest that borneol is a key component of A. koreana essential oil that has potential for mediating whitening and anti-wrinkle effects. |
| first_indexed | 2024-03-11T16:52:37Z |
| format | Article |
| id | doaj.art-a8152d1db16e4177814249202846d106 |
| institution | Directory Open Access Journal |
| issn | 1018-3647 |
| language | English |
| last_indexed | 2024-03-11T16:52:37Z |
| publishDate | 2023-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of King Saud University: Science |
| spelling | doaj.art-a8152d1db16e4177814249202846d1062023-10-21T04:22:11ZengElsevierJournal of King Saud University: Science1018-36472023-11-01358102886Borneol facilitates the whitening and anti-wrinkle effect of the essential oil extracted from Abies koreana needlesIl-Kwon Kim0Bomi Kim1Byeong-Wook Song2Sang Woo Kim3Dongsoo Kim4Jung Hwa Kang5Sung Hwan Hwang6Ki-Chul Hwang7Seahyoung Lee8Institute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do 210-701, Republic of KoreaInstitute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do 210-701, Republic of KoreaInstitute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do 210-701, Republic of KoreaInstitute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do 210-701, Republic of KoreaIMMUNISBIO Co. Ltd, B2F MTP Mall, International St. Mary’s Hospital, Incheon Metropolitan City 22711, Republic of KoreaIMMUNISBIO Co. Ltd, B2F MTP Mall, International St. Mary’s Hospital, Incheon Metropolitan City 22711, Republic of KoreaIMMUNISBIO Co. Ltd, B2F MTP Mall, International St. Mary’s Hospital, Incheon Metropolitan City 22711, Republic of KoreaInstitute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do 210-701, Republic of KoreaInstitute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do 210-701, Republic of Korea; Corresponding author.It has been reported that the essential oil extracted from Abies koreana has skin-improving activity, such as anti-wrinkle and whitening effect. However, the key ingredients that facilitate such biological activity has not been fully elucidated. In the present study, to identify the key skin-improving component(s) of the A. koreana essential oil, 10 sequentially fractioned essential oil from A. koreana pine by hydrodistillation were examined for their effect on tyrosinase activity. Out of 10 fractions, only 1 fraction significantly suppressed tyrosinase activity, and subsequent GC/MS analysis indicated that borneol and its acetate ester, bornyl acetate, were unique to the effective fraction, suggesting they are responsible for the skin-improving activity of the essential oil from A. koreana. The biological activity of borneol was evaluated, and borneol significantly inhibited ultraviolet irradiation-induced tyrosinase and matrix metalloproteinase 1 activity while maintain collagen type I synthesis. The results of this study suggest that borneol is a key component of A. koreana essential oil that has potential for mediating whitening and anti-wrinkle effects.http://www.sciencedirect.com/science/article/pii/S1018364723003488Abies KoreanaEssential oilWhiteningAnti-wrinkle |
| spellingShingle | Il-Kwon Kim Bomi Kim Byeong-Wook Song Sang Woo Kim Dongsoo Kim Jung Hwa Kang Sung Hwan Hwang Ki-Chul Hwang Seahyoung Lee Borneol facilitates the whitening and anti-wrinkle effect of the essential oil extracted from Abies koreana needles Journal of King Saud University: Science Abies Koreana Essential oil Whitening Anti-wrinkle |
| title | Borneol facilitates the whitening and anti-wrinkle effect of the essential oil extracted from Abies koreana needles |
| title_full | Borneol facilitates the whitening and anti-wrinkle effect of the essential oil extracted from Abies koreana needles |
| title_fullStr | Borneol facilitates the whitening and anti-wrinkle effect of the essential oil extracted from Abies koreana needles |
| title_full_unstemmed | Borneol facilitates the whitening and anti-wrinkle effect of the essential oil extracted from Abies koreana needles |
| title_short | Borneol facilitates the whitening and anti-wrinkle effect of the essential oil extracted from Abies koreana needles |
| title_sort | borneol facilitates the whitening and anti wrinkle effect of the essential oil extracted from abies koreana needles |
| topic | Abies Koreana Essential oil Whitening Anti-wrinkle |
| url | http://www.sciencedirect.com/science/article/pii/S1018364723003488 |
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