Microwave assisted solvent-free mannich bases: synthesis, characterization and effects of these compounds on HCA I and HCA II isozymes

Microwave assisted solvent-free mannich bases: synthesis, characterization and effects of these compounds on HCA I and HCA II isozymes

Mannich bases (2a–d) of aromatic amines were synthesized by using a conventional microwave technique under solvent-free conditions and characterized by IR and NMR (1H and 13C) and elemental analysis. The inhibitory effects of the synthesized Mannich bases were examined in vitro by using hydratase a...

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Bibliographic Details
Main Authors: Bülent Büyükkıdan, Nurgün Büyükkıdan, Metin Bülbül, Melek Yılmaz, Evren Derrun Arslanbay, Ekrem Tunca
Format: Article
Language:English
Published: Society of Chemists and Technologists of Macedonia 2021-05-01
Series:Macedonian Journal of Chemistry and Chemical Engineering
Subjects:
Activator
carbonic anhydrase
glaucoma
isozyme
Online Access:https://mjcce.org.mk/index.php/MJCCE/article/view/1968

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