Three Binding Conformations of BIO124 in the Pocket of the PICK1 PDZ Domain

The PDZ family has drawn attention as possible drug targets because of the domains’ wide ranges of function and highly conserved binding pockets. The PICK1 PDZ domain has been proposed as a possible drug target because the interactions between the PICK1 PDZ domain and the GluA2 subunit of the AMPA r...

全面介绍

书目详细资料
Main Authors: Amy O. Stevens, Samuel Luo, Yi He
格式: 文件
语言:English
出版: MDPI AG 2022-08-01
丛编:Cells
主题:
在线阅读:https://www.mdpi.com/2073-4409/11/15/2451