Salivary IgA and IgE levels in healthy subjects: relation to age and gender
It has been reported that the immune system undergoes age and gender changes. The aim of this study was to investigate the age- and gender-dependent changes of salivary IgA and IgE levels among healthy subjects. A total of 203 healthy individuals (aged 1-70 years) were enrolled in the study. Two mil...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Pesquisa Odontológica
2010-03-01
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| Series: | Brazilian Oral Research |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242010000100004 |
| _version_ | 1831689873157783552 |
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| author | Abdollah Jafarzadeh Mostafa Sadeghi Gholamreza Asadi Karam Reza Vazirinejad |
| author_facet | Abdollah Jafarzadeh Mostafa Sadeghi Gholamreza Asadi Karam Reza Vazirinejad |
| author_sort | Abdollah Jafarzadeh |
| collection | DOAJ |
| description | It has been reported that the immune system undergoes age and gender changes. The aim of this study was to investigate the age- and gender-dependent changes of salivary IgA and IgE levels among healthy subjects. A total of 203 healthy individuals (aged 1-70 years) were enrolled in the study. Two milliliters of saliva were collected from all participants, and salivary IgA and IgE levels were measured by the ELISA technique. Mean salivary IgA levels were significantly higher in subjects aged 11-20 years as compared to subjects aged 1-10 years (P < 0.01). Mean salivary IgA levels increased with age up to the age of 60 years, and then slightly decreased in subjects aged 61-70 years. The frequency of subjects with detectable levels of salivary IgE and mean salivary IgE levels gradually increased with age, with maximum levels being observed in the 31-40 years age group and not changing significantly thereafter. The mean levels of salivary IgA and IgE in adults were significantly higher than those observed in children (P < 0.00001 and P < 0.05, respectively). No significant differences were observed between men and women regarding both salivary immunoglobulins. These results showed age-dependent changes of the salivary IgA and IgE levels. Gender had no effect on the salivary levels of IgA and IgE. |
| first_indexed | 2024-12-20T10:58:30Z |
| format | Article |
| id | doaj.art-a81b35e764fb4383ab0323dcf906dc73 |
| institution | Directory Open Access Journal |
| issn | 1806-8324 |
| language | English |
| last_indexed | 2024-12-20T10:58:30Z |
| publishDate | 2010-03-01 |
| publisher | Sociedade Brasileira de Pesquisa Odontológica |
| record_format | Article |
| series | Brazilian Oral Research |
| spelling | doaj.art-a81b35e764fb4383ab0323dcf906dc732022-12-21T19:43:05ZengSociedade Brasileira de Pesquisa OdontológicaBrazilian Oral Research1806-83242010-03-01241212710.1590/S1806-83242010000100004Salivary IgA and IgE levels in healthy subjects: relation to age and genderAbdollah JafarzadehMostafa SadeghiGholamreza Asadi KaramReza VazirinejadIt has been reported that the immune system undergoes age and gender changes. The aim of this study was to investigate the age- and gender-dependent changes of salivary IgA and IgE levels among healthy subjects. A total of 203 healthy individuals (aged 1-70 years) were enrolled in the study. Two milliliters of saliva were collected from all participants, and salivary IgA and IgE levels were measured by the ELISA technique. Mean salivary IgA levels were significantly higher in subjects aged 11-20 years as compared to subjects aged 1-10 years (P < 0.01). Mean salivary IgA levels increased with age up to the age of 60 years, and then slightly decreased in subjects aged 61-70 years. The frequency of subjects with detectable levels of salivary IgE and mean salivary IgE levels gradually increased with age, with maximum levels being observed in the 31-40 years age group and not changing significantly thereafter. The mean levels of salivary IgA and IgE in adults were significantly higher than those observed in children (P < 0.00001 and P < 0.05, respectively). No significant differences were observed between men and women regarding both salivary immunoglobulins. These results showed age-dependent changes of the salivary IgA and IgE levels. Gender had no effect on the salivary levels of IgA and IgE.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242010000100004SalivaImmunoglobulin AImmunoglobulin EAdultChild |
| spellingShingle | Abdollah Jafarzadeh Mostafa Sadeghi Gholamreza Asadi Karam Reza Vazirinejad Salivary IgA and IgE levels in healthy subjects: relation to age and gender Brazilian Oral Research Saliva Immunoglobulin A Immunoglobulin E Adult Child |
| title | Salivary IgA and IgE levels in healthy subjects: relation to age and gender |
| title_full | Salivary IgA and IgE levels in healthy subjects: relation to age and gender |
| title_fullStr | Salivary IgA and IgE levels in healthy subjects: relation to age and gender |
| title_full_unstemmed | Salivary IgA and IgE levels in healthy subjects: relation to age and gender |
| title_short | Salivary IgA and IgE levels in healthy subjects: relation to age and gender |
| title_sort | salivary iga and ige levels in healthy subjects relation to age and gender |
| topic | Saliva Immunoglobulin A Immunoglobulin E Adult Child |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1806-83242010000100004 |
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