Multicenter intestinal current measurements in rectal biopsies from CF and non-CF subjects to monitor CFTR function.

Multicenter intestinal current measurements in rectal biopsies from CF and non-CF subjects to monitor CFTR function.

Intestinal current measurements (ICM) from rectal biopsies are a sensitive means to detect cystic fibrosis transmembrane conductance regulator (CFTR) function, but have not been optimized for multicenter use. We piloted multicenter standard operating procedures (SOPs) to detect CFTR activity by ICM...

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Bibliographic Details
Main Authors: John P Clancy, Rhonda D Szczesniak, Melissa A Ashlock, Sarah E Ernst, Lijuan Fan, Douglas B Hornick, Philip H Karp, Umer Khan, James Lymp, Alicia J Ostmann, Amir Rezayat, Timothy D Starner, Shajan P Sugandha, Hongtao Sun, Nancy Quinney, Scott H Donaldson, Steven M Rowe, Sherif E Gabriel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3769519?pdf=render

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