Mechanistic study on the alleviation of postmenopausal osteoporosis by Lactobacillus acidophilus through butyrate-mediated inhibition of osteoclast activity

Mechanistic study on the alleviation of postmenopausal osteoporosis by Lactobacillus acidophilus through butyrate-mediated inhibition of osteoclast activity

Abstract In China, traditional medications for osteoporosis have significant side effects, low compliance, and high costs, making it urgent to explore new treatment options. Probiotics have demonstrated superiority in the treatment of various chronic diseases, and the reduction of bone mass in postm...

Full description

Bibliographic Details
Main Authors: Junjie Dong, Guizhao Shu, Jin Yang, Bing Wang, Lingqiang Chen, Zhiqiang Gong, Xiaofeng Zhang
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Postmenopausal osteoporosis
Lactobacillus acidophilus
Butyrate
Osteoclasts
B cells
Intestinal bone axis
Online Access:https://doi.org/10.1038/s41598-024-57122-x

Similar Items

Similar Items