Efficacy of intraoperative dexmedetomidine infusion on visualization of the surgical field in endoscopic sinus surgery
BackgroundIn endoscopic sinus surgery, visualization of the surgical field is a major concern, as surgical bleeding is the cause of many complications. The purpose of this study was to compare the effects of dexmedetomidine and remifentanil on the visualization of the surgical field in endoscopic si...
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Korean Society of Anesthesiologists
2015-10-01
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| Series: | Korean Journal of Anesthesiology |
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| Online Access: | http://ekja.org/upload/pdf/kjae-68-449.pdf |
| _version_ | 1818971805421928448 |
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| author | Hyunzu Kim Sang-Hee Ha Chang-Hoon Kim Sang-Hoon Lee Seung-Ho Choi |
| author_facet | Hyunzu Kim Sang-Hee Ha Chang-Hoon Kim Sang-Hoon Lee Seung-Ho Choi |
| author_sort | Hyunzu Kim |
| collection | DOAJ |
| description | BackgroundIn endoscopic sinus surgery, visualization of the surgical field is a major concern, as surgical bleeding is the cause of many complications. The purpose of this study was to compare the effects of dexmedetomidine and remifentanil on the visualization of the surgical field in endoscopic sinus surgery.MethodsForty-three patients were prospectively enrolled and randomly allocated to the dexmedetomidine or remifentanil group and general anesthesia was induced and maintained using a propofol target-controlled infusion. In the dexmedetomidine group, dexmedetomidine was loaded for 5 min and a continuous infusion was administered. In the remifentanil group, a remifentanil target-controlled infusion was used. After completion of the operation, the satisfaction with the visualization of the surgical field was assessed on a numeric rating scale, from 0 (= worst) to 10 (= best). The mean blood pressure, heart rate, recovery profiles, and postoperative pain score were recorded.ResultsSatisfaction score for visualization by numeric rating scale was not significantly different between the two groups (P = 0.95). There were no differences in the mean blood pressure and heart rate. The extubation time was significantly shorter in the dexmedetomidine group (8.4 ± 1.8 min) than in the remifentanil group (11.9 ± 5.4 min) (P = 0.04). Except for the extubation time, the recovery profiles of the two groups were comparable.ConclusionsContinuous infusions of dexmedetomidine provide a similar visualization of the surgical field and hemodynamic stability as remifentanil target-controlled infusions in patients undergoing endoscopic sinus surgery. |
| first_indexed | 2024-12-20T14:58:13Z |
| format | Article |
| id | doaj.art-a82ba5e770e0493193d28cc2d421cdde |
| institution | Directory Open Access Journal |
| issn | 2005-6419 2005-7563 |
| language | English |
| last_indexed | 2024-12-20T14:58:13Z |
| publishDate | 2015-10-01 |
| publisher | Korean Society of Anesthesiologists |
| record_format | Article |
| series | Korean Journal of Anesthesiology |
| spelling | doaj.art-a82ba5e770e0493193d28cc2d421cdde2022-12-21T19:36:44ZengKorean Society of AnesthesiologistsKorean Journal of Anesthesiology2005-64192005-75632015-10-0168544945410.4097/kjae.2015.68.5.4498106Efficacy of intraoperative dexmedetomidine infusion on visualization of the surgical field in endoscopic sinus surgeryHyunzu Kim0Sang-Hee Ha1Chang-Hoon Kim2Sang-Hoon Lee3Seung-Ho Choi4Department of Anesthesiology and Pain Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea.Department of Otorhinolaryngology, Medical Research Center, Yonsei University College of Medicine, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea.BackgroundIn endoscopic sinus surgery, visualization of the surgical field is a major concern, as surgical bleeding is the cause of many complications. The purpose of this study was to compare the effects of dexmedetomidine and remifentanil on the visualization of the surgical field in endoscopic sinus surgery.MethodsForty-three patients were prospectively enrolled and randomly allocated to the dexmedetomidine or remifentanil group and general anesthesia was induced and maintained using a propofol target-controlled infusion. In the dexmedetomidine group, dexmedetomidine was loaded for 5 min and a continuous infusion was administered. In the remifentanil group, a remifentanil target-controlled infusion was used. After completion of the operation, the satisfaction with the visualization of the surgical field was assessed on a numeric rating scale, from 0 (= worst) to 10 (= best). The mean blood pressure, heart rate, recovery profiles, and postoperative pain score were recorded.ResultsSatisfaction score for visualization by numeric rating scale was not significantly different between the two groups (P = 0.95). There were no differences in the mean blood pressure and heart rate. The extubation time was significantly shorter in the dexmedetomidine group (8.4 ± 1.8 min) than in the remifentanil group (11.9 ± 5.4 min) (P = 0.04). Except for the extubation time, the recovery profiles of the two groups were comparable.ConclusionsContinuous infusions of dexmedetomidine provide a similar visualization of the surgical field and hemodynamic stability as remifentanil target-controlled infusions in patients undergoing endoscopic sinus surgery.http://ekja.org/upload/pdf/kjae-68-449.pdfblood lossdexmedetomidineremifentanilsinusitis |
| spellingShingle | Hyunzu Kim Sang-Hee Ha Chang-Hoon Kim Sang-Hoon Lee Seung-Ho Choi Efficacy of intraoperative dexmedetomidine infusion on visualization of the surgical field in endoscopic sinus surgery Korean Journal of Anesthesiology blood loss dexmedetomidine remifentanil sinusitis |
| title | Efficacy of intraoperative dexmedetomidine infusion on visualization of the surgical field in endoscopic sinus surgery |
| title_full | Efficacy of intraoperative dexmedetomidine infusion on visualization of the surgical field in endoscopic sinus surgery |
| title_fullStr | Efficacy of intraoperative dexmedetomidine infusion on visualization of the surgical field in endoscopic sinus surgery |
| title_full_unstemmed | Efficacy of intraoperative dexmedetomidine infusion on visualization of the surgical field in endoscopic sinus surgery |
| title_short | Efficacy of intraoperative dexmedetomidine infusion on visualization of the surgical field in endoscopic sinus surgery |
| title_sort | efficacy of intraoperative dexmedetomidine infusion on visualization of the surgical field in endoscopic sinus surgery |
| topic | blood loss dexmedetomidine remifentanil sinusitis |
| url | http://ekja.org/upload/pdf/kjae-68-449.pdf |
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