Signal transduction and activation of the NADPH oxidase in eosinophils

Signal transduction and activation of the NADPH oxidase in eosinophils

Activation of the eosinophil NADPH oxidase and the subsequent release of toxic oxygen radicals has been implicated in the mechanism of parasite killing and inflammation. At present, little is known of the signal transduction pathway that govern agonist-induced activation of the respiratory burst and...

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Bibliographic Details
Main Authors: Mark A Lindsay, Mark A Giembycz
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 1997-12-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
leukotriene B4
eosinophil
NADPH oxidase
signal transduction
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761997000800016

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