Snail-regulated exosomal microRNA-21 suppresses NLRP3 inflammasome activity to enhance cisplatin resistance

Background Compared with the precise targeting of drug-resistant mutant cancer cells, strategies for eliminating non-genetic adaptation-mediated resistance are limited. The pros and cons of the existence of inflammasomes in cancer have been reported. Nevertheless, the dynamic response of inflammasom...

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Bibliographic Details
Main Authors: Dennis Shin-Shian Hsu, Muh-Hwa Yang, Po-Han Lin, Han-Ying Cheng, Chia-Hsin Hsieh, Yu-Tung Chen, Shyh-Kuan Tai, Pen-Yuan Chu
Format: Article
Language:English
Published: BMJ Publishing Group 2022-08-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/10/8/e004832.full