Elucidation of the Mechanism Underlying the Anti-Inflammatory Properties of (S)-(+)-Carvone Identifies a Novel Class of Sirtuin-1 Activators in a Murine Macrophage Cell Line

Elucidation of the Mechanism Underlying the Anti-Inflammatory Properties of (S)-(+)-Carvone Identifies a Novel Class of Sirtuin-1 Activators in a Murine Macrophage Cell Line

The signaling pathways involved in age-related inflammation are increasingly recognized as targets for the development of preventive and therapeutic strategies. Our previous study elucidated the structure–activity relationship of monoterpene compounds derived from <i>p</i>-menthane as po...

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Bibliographic Details
Main Authors: Cátia Sousa, Bruno Miguel Neves, Alcino Jorge Leitão, Alexandrina Ferreira Mendes
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biomedicines
Subjects:
aging
inflammation
monoterpene
NF-κB
Sirtuin-1
Sirtuin-1 activating compound
Online Access:https://www.mdpi.com/2227-9059/9/7/777

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