Increased clonal hematopoiesis involving DNA damage response genes in patients undergoing lung transplantation

Increased clonal hematopoiesis involving DNA damage response genes in patients undergoing lung transplantation

BACKGROUND Cellular stressors influence the development of clonal hematopoiesis (CH). We hypothesized that environmental, inflammatory, and genotoxic stresses drive the emergence of CH in lung transplant recipients. METHODS We performed a cross-sectional cohort study of 85 lung transplant recipients...

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Bibliographic Details
Main Authors: Laneshia K. Tague, Karolyn A. Oetjen, Anirudh Mahadev, Matthew J. Walter, Hephzibah Anthony, Daniel Kreisel, Daniel C. Link, Andrew E. Gelman
Format: Article
Language:English
Published: American Society for Clinical investigation 2023-04-01
Series:JCI Insight
Subjects:
Genetics
Transplantation
Online Access:https://doi.org/10.1172/jci.insight.165609

Internet

https://doi.org/10.1172/jci.insight.165609

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