Regulation of immune responses by the neonatal Fc receptor and its therapeutic implications

Regulation of immune responses by the neonatal Fc receptor and its therapeutic implications

As a single receptor, the neonatal Fc receptor (FcRn) is critically involved in regulating albumin and IgG serum concentrations by protecting these two ligands from degradation. In addition to these essential homeostatic functions, FcRn possesses important functions in regulating immune responses th...

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Bibliographic Details
Main Authors: Timo eRath, Kristi eBaker, Michal ePyzik, Richard S. Blumberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Immunology
Subjects:
Antigen Presentation
Immunoglobulin G
mucosal immunology
Neonatal Fc Receptor (FcRn)
albumin
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00664/full

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