Genome wide DNA copy number analysis of serous type ovarian carcinomas identifies genetic markers predictive of clinical outcome.

Genome wide DNA copy number analysis of serous type ovarian carcinomas identifies genetic markers predictive of clinical outcome.

Ovarian cancer is the fifth leading cause of cancer death in women. Ovarian cancers display a high degree of complex genetic alterations involving many oncogenes and tumor suppressor genes. Analysis of the association between genetic alterations and clinical endpoints such as survival will lead to i...

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Main Authors: David A Engler, Sumeet Gupta, Whitfield B Growdon, Ronny I Drapkin, Mai Nitta, Petra A Sergent, Serena F Allred, Jenny Gross, Michael T Deavers, Wen-Lin Kuo, Beth Y Karlan, Bo R Rueda, Sandra Orsulic, David M Gershenson, Michael J Birrer, Joe W Gray, Gayatry Mohapatra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3280266?pdf=render

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