Expression of progesterone receptor membrane component-1 in bovine reproductive system during estrous cycle
Several reports suggest the participation of progesterone receptor membrane component 1 (PGRMC1) in progesterone signaling in the reproductive system. This study aimed at investigating the presence and localization of PGRMC1 in bovine ovary, oviduct and uterus, during the follicular and luteal phase...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2011-09-01
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| Series: | European Journal of Histochemistry |
| Subjects: | |
| Online Access: | http://www.ejh.it/index.php/ejh/article/view/1905 |
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| author | A.M. Luciano D. Corbani V. Lodde I. Tessaro F. Franciosi J.J. Peluso S. Modina |
| author_facet | A.M. Luciano D. Corbani V. Lodde I. Tessaro F. Franciosi J.J. Peluso S. Modina |
| author_sort | A.M. Luciano |
| collection | DOAJ |
| description | Several reports suggest the participation of progesterone receptor membrane component 1 (PGRMC1) in progesterone signaling in the reproductive system. This study aimed at investigating the presence and localization of PGRMC1 in bovine ovary, oviduct and uterus, during the follicular and luteal phases of the estrous cycle. In the ovary, PGRMC1 has been detected in surface germinal epithelium, granulosa cells, theca cells and in the germinal vesicle of the oocytesat all stages of folliculogenesis. In the <em>corpus luteum</em> the expression of PGRMC1 was influenced by the stage of the estrous cycle. In the oviducts and in the uterus horns, PGRMC1 was immunolocalized in the luminal epithelium, in the muscle layer cells and in the endothelial cells. In the uterus, PGRMC1 was intensely localized also in the glandular endometrium. However, in the oviducts and in the uterus horns, the localization of PGRMC1 was independent on the stage of the estrous cycle and on whether evaluating the ipsilateral or the contralateral organ. In conclusion, the present immunohistochemical study showed that PGRMC1 is located in various compartments of the bovine female reproductive organs. With the exception of the <em>corpora lutea</em>, PGRMC1 localization showed similar pattern during different stage of the estrous cycle. |
| first_indexed | 2024-04-13T08:03:51Z |
| format | Article |
| id | doaj.art-a84038da8d7e489aaa1c11c092e54b98 |
| institution | Directory Open Access Journal |
| issn | 1121-760X 2038-8306 |
| language | English |
| last_indexed | 2024-04-13T08:03:51Z |
| publishDate | 2011-09-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | European Journal of Histochemistry |
| spelling | doaj.art-a84038da8d7e489aaa1c11c092e54b982022-12-22T02:55:14ZengPAGEPress PublicationsEuropean Journal of Histochemistry1121-760X2038-83062011-09-01553e27e2710.4081/ejh.2011.e271221Expression of progesterone receptor membrane component-1 in bovine reproductive system during estrous cycleA.M. Luciano0D. Corbani1V. Lodde2I. Tessaro3F. Franciosi4J.J. Peluso5S. Modina6University of Milan, Department of Animal SciencesUniversity of MilanUniversity of MilanUniversity of MilanUniversity of MilanUniversity of ConnecticuyUniversity of MilanSeveral reports suggest the participation of progesterone receptor membrane component 1 (PGRMC1) in progesterone signaling in the reproductive system. This study aimed at investigating the presence and localization of PGRMC1 in bovine ovary, oviduct and uterus, during the follicular and luteal phases of the estrous cycle. In the ovary, PGRMC1 has been detected in surface germinal epithelium, granulosa cells, theca cells and in the germinal vesicle of the oocytesat all stages of folliculogenesis. In the <em>corpus luteum</em> the expression of PGRMC1 was influenced by the stage of the estrous cycle. In the oviducts and in the uterus horns, PGRMC1 was immunolocalized in the luminal epithelium, in the muscle layer cells and in the endothelial cells. In the uterus, PGRMC1 was intensely localized also in the glandular endometrium. However, in the oviducts and in the uterus horns, the localization of PGRMC1 was independent on the stage of the estrous cycle and on whether evaluating the ipsilateral or the contralateral organ. In conclusion, the present immunohistochemical study showed that PGRMC1 is located in various compartments of the bovine female reproductive organs. With the exception of the <em>corpora lutea</em>, PGRMC1 localization showed similar pattern during different stage of the estrous cycle.http://www.ejh.it/index.php/ejh/article/view/1905Uterus, oviduct, ovary, corpus luteum, follicle, oocyte, progesterone receptor |
| spellingShingle | A.M. Luciano D. Corbani V. Lodde I. Tessaro F. Franciosi J.J. Peluso S. Modina Expression of progesterone receptor membrane component-1 in bovine reproductive system during estrous cycle European Journal of Histochemistry Uterus, oviduct, ovary, corpus luteum, follicle, oocyte, progesterone receptor |
| title | Expression of progesterone receptor membrane component-1 in bovine reproductive system during estrous cycle |
| title_full | Expression of progesterone receptor membrane component-1 in bovine reproductive system during estrous cycle |
| title_fullStr | Expression of progesterone receptor membrane component-1 in bovine reproductive system during estrous cycle |
| title_full_unstemmed | Expression of progesterone receptor membrane component-1 in bovine reproductive system during estrous cycle |
| title_short | Expression of progesterone receptor membrane component-1 in bovine reproductive system during estrous cycle |
| title_sort | expression of progesterone receptor membrane component 1 in bovine reproductive system during estrous cycle |
| topic | Uterus, oviduct, ovary, corpus luteum, follicle, oocyte, progesterone receptor |
| url | http://www.ejh.it/index.php/ejh/article/view/1905 |
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