Utilization of hypoxia-derived gene signatures to predict clinical outcomes and immune checkpoint blockade therapy responses in prostate cancer

Utilization of hypoxia-derived gene signatures to predict clinical outcomes and immune checkpoint blockade therapy responses in prostate cancer

Background: Increasing evidences show a clinical significance in the interaction between hypoxia and prostate cancer. However, reliable prognostic signatures based on hypoxia have not been established yet.Methods: We screened hypoxia-related gene modules by weighted gene co-expression network analys...

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Bibliographic Details
Main Authors: Minhua Chen, Zhang Chen, Zongbin Lin, Xiang Ding, Tianyu Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Genetics
Subjects:
prostate cancer
hypoxia
immune checkpoint blockade
prognostic
outcome
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.922074/full

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