Cryoglobulinemic vasculitis in chronic hepatitis C: Genetic aspects
Cryoglobulinemia (CG) is detected in more than 50% of patients with chronic hepatitis C (CHC); however, only 15—25% of them develop cryoglobulinemic vasculitis (CV) that is a systemic vasculitis due to the formation of immune deposits, which affects small (less than medium-sized) vessels and which i...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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"Consilium Medicum" Publishing house
2017-04-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/viewFile/32251/pdf |
| _version_ | 1818041097523298304 |
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| author | M G Artemova D T Abdurakhmanov |
| author_facet | M G Artemova D T Abdurakhmanov |
| author_sort | M G Artemova |
| collection | DOAJ |
| description | Cryoglobulinemia (CG) is detected in more than 50% of patients with chronic hepatitis C (CHC); however, only 15—25% of them develop cryoglobulinemic vasculitis (CV) that is a systemic vasculitis due to the formation of immune deposits, which affects small (less than medium-sized) vessels and which is frequently fatal for the patient. The causes of CG only in some patients with CHC and the pathogenesis of CV remain unstudied; however, the accumulated data allow one to identify the special contribution of the patient’s genetic factors to the development of the disease. The paper considers the genetic aspects of the development of CG and CV in CHC. |
| first_indexed | 2024-12-10T08:25:00Z |
| format | Article |
| id | doaj.art-a841852acbe142db95cbb7b0a6b01e9e |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-10T08:25:00Z |
| publishDate | 2017-04-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-a841852acbe142db95cbb7b0a6b01e9e2022-12-22T01:56:16Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422017-04-0189411011410.17116/terarkh2017894110-11429251Cryoglobulinemic vasculitis in chronic hepatitis C: Genetic aspectsM G ArtemovaD T AbdurakhmanovCryoglobulinemia (CG) is detected in more than 50% of patients with chronic hepatitis C (CHC); however, only 15—25% of them develop cryoglobulinemic vasculitis (CV) that is a systemic vasculitis due to the formation of immune deposits, which affects small (less than medium-sized) vessels and which is frequently fatal for the patient. The causes of CG only in some patients with CHC and the pathogenesis of CV remain unstudied; however, the accumulated data allow one to identify the special contribution of the patient’s genetic factors to the development of the disease. The paper considers the genetic aspects of the development of CG and CV in CHC.https://ter-arkhiv.ru/0040-3660/article/viewFile/32251/pdfhepatitis c viruscryoglobulinemiacryoglobulinemic vasculitisgenetic aspects |
| spellingShingle | M G Artemova D T Abdurakhmanov Cryoglobulinemic vasculitis in chronic hepatitis C: Genetic aspects Терапевтический архив hepatitis c virus cryoglobulinemia cryoglobulinemic vasculitis genetic aspects |
| title | Cryoglobulinemic vasculitis in chronic hepatitis C: Genetic aspects |
| title_full | Cryoglobulinemic vasculitis in chronic hepatitis C: Genetic aspects |
| title_fullStr | Cryoglobulinemic vasculitis in chronic hepatitis C: Genetic aspects |
| title_full_unstemmed | Cryoglobulinemic vasculitis in chronic hepatitis C: Genetic aspects |
| title_short | Cryoglobulinemic vasculitis in chronic hepatitis C: Genetic aspects |
| title_sort | cryoglobulinemic vasculitis in chronic hepatitis c genetic aspects |
| topic | hepatitis c virus cryoglobulinemia cryoglobulinemic vasculitis genetic aspects |
| url | https://ter-arkhiv.ru/0040-3660/article/viewFile/32251/pdf |
| work_keys_str_mv | AT mgartemova cryoglobulinemicvasculitisinchronichepatitiscgeneticaspects AT dtabdurakhmanov cryoglobulinemicvasculitisinchronichepatitiscgeneticaspects |