Genus <i>Amorphophallus</i>: A Comprehensive Overview on Phytochemistry, Ethnomedicinal Uses, and Pharmacological Activities
The genus <i>Amorphophallus</i> belongs to the family Araceae. Plants belonging to this genus are available worldwide and have been used in traditional medicines since ancient times, mainly in Ayurveda and Unani medical practices. <i>Amorphophallus</i> species are an abundant...
| Main Authors: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-11-01
|
| Series: | Plants |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2223-7747/12/23/3945 |
| _version_ | 1797399726084063232 |
|---|---|
| author | Fahadul Islam Rafiuddin Khan Labib Mehrukh Zehravi Mashia Subha Lami Rajib Das Laliteshwar Pratap Singh Jithendar Reddy Mandhadi P. Balan Jishan Khan Sharuk L. Khan Firzan Nainu Mohamed H. Nafady Safia Obaidur Rab Talha Bin Emran Polrat Wilairatana |
| author_facet | Fahadul Islam Rafiuddin Khan Labib Mehrukh Zehravi Mashia Subha Lami Rajib Das Laliteshwar Pratap Singh Jithendar Reddy Mandhadi P. Balan Jishan Khan Sharuk L. Khan Firzan Nainu Mohamed H. Nafady Safia Obaidur Rab Talha Bin Emran Polrat Wilairatana |
| author_sort | Fahadul Islam |
| collection | DOAJ |
| description | The genus <i>Amorphophallus</i> belongs to the family Araceae. Plants belonging to this genus are available worldwide and have been used in traditional medicines since ancient times, mainly in Ayurveda and Unani medical practices. <i>Amorphophallus</i> species are an abundant source of polyphenolic compounds; these are accountable for their pharmacological properties, such as their analgesic, neuroprotective, hepatoprotective, anti-inflammatory, anticonvulsant, antibacterial, antioxidant, anticancer, antiobesity, and immunomodulatory effects, as well as their ability to prevent gastrointestinal disturbance and reduce blood glucose. Moreover, <i>Amorphophallus</i> species contain numerous other classes of chemical compounds, such as alkaloids, steroids, fats and fixed oils, tannins, proteins, and carbohydrates, each of which contributes to the pharmacological effects for the treatment of acute rheumatism, tumors, lung swelling, asthma, vomiting, abdominal pain, and so on. Additionally, <i>Amorphophallus</i> species have been employed in numerous herbal formulations and pharmaceutical applications. There has been no extensive review conducted on the <i>Amorphophallus</i> genus as of yet, despite the fact that several experimental studies are being published regularly discussing these plants’ pharmacological properties. So, this review discusses in detail the pharmacological properties of <i>Amorphophallus</i> species. We also discuss phytochemical constituents in the <i>Amorphophallus</i> species and their ethnomedicinal uses and toxicological profiles. |
| first_indexed | 2024-03-09T01:45:13Z |
| format | Article |
| id | doaj.art-a84803b02071437cbbb62e0ecacde002 |
| institution | Directory Open Access Journal |
| issn | 2223-7747 |
| language | English |
| last_indexed | 2024-03-09T01:45:13Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Plants |
| spelling | doaj.art-a84803b02071437cbbb62e0ecacde0022023-12-08T15:23:43ZengMDPI AGPlants2223-77472023-11-011223394510.3390/plants12233945Genus <i>Amorphophallus</i>: A Comprehensive Overview on Phytochemistry, Ethnomedicinal Uses, and Pharmacological ActivitiesFahadul Islam0Rafiuddin Khan Labib1Mehrukh Zehravi2Mashia Subha Lami3Rajib Das4Laliteshwar Pratap Singh5Jithendar Reddy Mandhadi6P. Balan7Jishan Khan8Sharuk L. Khan9Firzan Nainu10Mohamed H. Nafady11Safia Obaidur Rab12Talha Bin Emran13Polrat Wilairatana14Department of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka 1207, BangladeshDepartment of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, BangladeshDepartment of Clinical Pharmacy, College of Dentistry & Pharmacy, Buraydah Private Colleges, Buraydah 51418, Saudi ArabiaDepartment of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, BangladeshDepartment of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka 1000, BangladeshDepartment of Pharmaceutical Chemistry, Narayan Institute of Pharmacy, Gopal Narayan Singh University, Sasaram 821305, IndiaDepartment of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Assam Down Town University (AdtU), Gandhinagar 781026, IndiaDepartment of Pharmaceutical Chemistry, The Erode College of Pharmacy, Erode 638112, IndiaDepartment of Pharmacy, International Islamic University Chittagong, Kumira, Chittagong 4318, BangladeshDepartment of Pharmaceutical Chemistry, N.B.S. Institute of Pharmacy, Ausa 413520, IndiaDepartment of Pharmacy, Faculty of Pharmacy, Hasanuddin University, Makassar 90245, IndonesiaFaculty of Applied Health Science Technology, Misr University for Science and Technology, Giza 12568, EgyptDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha 61421, Saudi ArabiaDepartment of Pharmacy, Faculty of Allied Health Sciences, Daffodil International University, Dhaka 1207, BangladeshDepartment of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, ThailandThe genus <i>Amorphophallus</i> belongs to the family Araceae. Plants belonging to this genus are available worldwide and have been used in traditional medicines since ancient times, mainly in Ayurveda and Unani medical practices. <i>Amorphophallus</i> species are an abundant source of polyphenolic compounds; these are accountable for their pharmacological properties, such as their analgesic, neuroprotective, hepatoprotective, anti-inflammatory, anticonvulsant, antibacterial, antioxidant, anticancer, antiobesity, and immunomodulatory effects, as well as their ability to prevent gastrointestinal disturbance and reduce blood glucose. Moreover, <i>Amorphophallus</i> species contain numerous other classes of chemical compounds, such as alkaloids, steroids, fats and fixed oils, tannins, proteins, and carbohydrates, each of which contributes to the pharmacological effects for the treatment of acute rheumatism, tumors, lung swelling, asthma, vomiting, abdominal pain, and so on. Additionally, <i>Amorphophallus</i> species have been employed in numerous herbal formulations and pharmaceutical applications. There has been no extensive review conducted on the <i>Amorphophallus</i> genus as of yet, despite the fact that several experimental studies are being published regularly discussing these plants’ pharmacological properties. So, this review discusses in detail the pharmacological properties of <i>Amorphophallus</i> species. We also discuss phytochemical constituents in the <i>Amorphophallus</i> species and their ethnomedicinal uses and toxicological profiles.https://www.mdpi.com/2223-7747/12/23/3945<i>Amorphophallus</i>Araceaetraditional medicineethnopharmacologyphytochemistryethnobotany |
| spellingShingle | Fahadul Islam Rafiuddin Khan Labib Mehrukh Zehravi Mashia Subha Lami Rajib Das Laliteshwar Pratap Singh Jithendar Reddy Mandhadi P. Balan Jishan Khan Sharuk L. Khan Firzan Nainu Mohamed H. Nafady Safia Obaidur Rab Talha Bin Emran Polrat Wilairatana Genus <i>Amorphophallus</i>: A Comprehensive Overview on Phytochemistry, Ethnomedicinal Uses, and Pharmacological Activities Plants <i>Amorphophallus</i> Araceae traditional medicine ethnopharmacology phytochemistry ethnobotany |
| title | Genus <i>Amorphophallus</i>: A Comprehensive Overview on Phytochemistry, Ethnomedicinal Uses, and Pharmacological Activities |
| title_full | Genus <i>Amorphophallus</i>: A Comprehensive Overview on Phytochemistry, Ethnomedicinal Uses, and Pharmacological Activities |
| title_fullStr | Genus <i>Amorphophallus</i>: A Comprehensive Overview on Phytochemistry, Ethnomedicinal Uses, and Pharmacological Activities |
| title_full_unstemmed | Genus <i>Amorphophallus</i>: A Comprehensive Overview on Phytochemistry, Ethnomedicinal Uses, and Pharmacological Activities |
| title_short | Genus <i>Amorphophallus</i>: A Comprehensive Overview on Phytochemistry, Ethnomedicinal Uses, and Pharmacological Activities |
| title_sort | genus i amorphophallus i a comprehensive overview on phytochemistry ethnomedicinal uses and pharmacological activities |
| topic | <i>Amorphophallus</i> Araceae traditional medicine ethnopharmacology phytochemistry ethnobotany |
| url | https://www.mdpi.com/2223-7747/12/23/3945 |
| work_keys_str_mv | AT fahadulislam genusiamorphophallusiacomprehensiveoverviewonphytochemistryethnomedicinalusesandpharmacologicalactivities AT rafiuddinkhanlabib genusiamorphophallusiacomprehensiveoverviewonphytochemistryethnomedicinalusesandpharmacologicalactivities AT mehrukhzehravi genusiamorphophallusiacomprehensiveoverviewonphytochemistryethnomedicinalusesandpharmacologicalactivities AT mashiasubhalami genusiamorphophallusiacomprehensiveoverviewonphytochemistryethnomedicinalusesandpharmacologicalactivities AT rajibdas genusiamorphophallusiacomprehensiveoverviewonphytochemistryethnomedicinalusesandpharmacologicalactivities AT laliteshwarpratapsingh genusiamorphophallusiacomprehensiveoverviewonphytochemistryethnomedicinalusesandpharmacologicalactivities AT jithendarreddymandhadi genusiamorphophallusiacomprehensiveoverviewonphytochemistryethnomedicinalusesandpharmacologicalactivities AT pbalan genusiamorphophallusiacomprehensiveoverviewonphytochemistryethnomedicinalusesandpharmacologicalactivities AT jishankhan genusiamorphophallusiacomprehensiveoverviewonphytochemistryethnomedicinalusesandpharmacologicalactivities AT sharuklkhan genusiamorphophallusiacomprehensiveoverviewonphytochemistryethnomedicinalusesandpharmacologicalactivities AT firzannainu genusiamorphophallusiacomprehensiveoverviewonphytochemistryethnomedicinalusesandpharmacologicalactivities AT mohamedhnafady genusiamorphophallusiacomprehensiveoverviewonphytochemistryethnomedicinalusesandpharmacologicalactivities AT safiaobaidurrab genusiamorphophallusiacomprehensiveoverviewonphytochemistryethnomedicinalusesandpharmacologicalactivities AT talhabinemran genusiamorphophallusiacomprehensiveoverviewonphytochemistryethnomedicinalusesandpharmacologicalactivities AT polratwilairatana genusiamorphophallusiacomprehensiveoverviewonphytochemistryethnomedicinalusesandpharmacologicalactivities |