Enantioselective Total Synthesis of (+)-Lyngbyabellin M

Enantioselective Total Synthesis of (+)-Lyngbyabellin M

Lyngbyabellin M is a non-ribosomal peptide synthetase/polyketide synthase derived metabolite isolated from the cyanobacterium M. bouillonii displaying thiazole rings and a distinct chlorinated octanoic acid chain. Its absolute configuration was proposed based on the comparison of its spectroscopic d...

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Bibliographic Details
Main Authors: Rodrigo V. Pirovani, Gilmar A. Brito, Rosimeire C. Barcelos, Ronaldo A. Pilli
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Marine Drugs
Subjects:
lyngbyabellin M
total synthesis
chiral thiazoles
stereoselective anti aldol
Online Access:http://www.mdpi.com/1660-3397/13/6/3309

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