Identification of an intronic enhancer regulating RANKL expression in osteocytic cells
Abstract The bony skeleton is continuously renewed throughout adult life by the bone remodeling process, in which old or damaged bone is removed by osteoclasts via largely unknown mechanisms. Osteocytes regulate bone remodeling by producing the osteoclast differentiation factor RANKL (encoded by the...
Main Authors: | Minglu Yan, Masayuki Tsukasaki, Ryunosuke Muro, Yutaro Ando, Kazutaka Nakamura, Noriko Komatsu, Takeshi Nitta, Tadashi Okamura, Kazuo Okamoto, Hiroshi Takayanagi |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-08-01
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Series: | Bone Research |
Online Access: | https://doi.org/10.1038/s41413-023-00277-6 |
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