Immune landscape in rejection of renal transplantation revealed by high-throughput single-cell RNA sequencing

Immune landscape in rejection of renal transplantation revealed by high-throughput single-cell RNA sequencing

Background: The role of the cellular level in kidney transplant rejection is unclear, and single-cell RNA sequencing (scRNA-seq) can reveal the single-cell landscape behind rejection of human kidney allografts at the single-cell level.Methods: High-quality transcriptomes were generated from scRNA-se...

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Bibliographic Details
Main Authors: Ning Wen, Jihua Wu, Haibin Li, Jixiang Liao, Liugen Lan, Xiawei Yang, Guangyi Zhu, Zhiying Lei, Jianhui Dong, Xuyong Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
renal transplantation
rejection
single-cell RNA sequencing
immune landscape
pro-inflammatory response
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1208566/full

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