Analysis of Spatial Organization of Suppressive Myeloid Cells and Effector T Cells in Colorectal Cancer—A Potential Tool for Discovering Prognostic Biomarkers in Clinical Research

Analysis of Spatial Organization of Suppressive Myeloid Cells and Effector T Cells in Colorectal Cancer—A Potential Tool for Discovering Prognostic Biomarkers in Clinical Research

The development and progression of solid tumors such as colorectal cancer (CRC) are known to be affected by the immune system and cell types such as T cells, natural killer (NK) cells, and natural killer T (NKT) cells are emerging as interesting targets for immunotherapy and clinical biomarker resea...

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Bibliographic Details
Main Authors: Natalie Zwing, Henrik Failmezger, Chia-Huey Ooi, Derrek P. Hibar, Marta Cañamero, Bruno Gomes, Fabien Gaire, Konstanty Korski
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
computational pathology
spatial statistics
tumor immune microenvironment
suppressive myeloid cells
T cells
colorectal cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.550250/full

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