Transcriptomic and Lipidomic Profiles in Nasal Polyps of Glucocorticoid Responders and Non-Responders: Before and After Treatment

Transcriptomic and Lipidomic Profiles in Nasal Polyps of Glucocorticoid Responders and Non-Responders: Before and After Treatment

Background: The pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) and mechanisms underlying different responses to systemic glucocorticoids (GC) remain unclear. The major aim of this study was to explore the transcriptomic and oxidative lipidomic signatures and the effects of GC in p...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Zhenzhen Zhu, Weiqing Wang, Yang Zha, Xiaowei Wang, Lei Wang, Jinbo Han, Jianmin Zhang, Wei Lv
Fformat:	Erthygl
Iaith:	English
Cyhoeddwyd:	Frontiers Media S.A. 2022-01-01
Cyfres:	Frontiers in Pharmacology
Pynciau:	chronic rhinosinusitis with nasal polyps cilia glucocorticoids oxylipid mediator transcriptomic sequencing
Mynediad Ar-lein:	https://www.frontiersin.org/articles/10.3389/fphar.2021.814953/full

Eitemau Tebyg

Effect of short-course glucocorticoid application on patients with chronic rhinosinusitis with nasal polyps
gan: Zhaofeng Xu, et al.
Cyhoeddwyd: (2020-06-01)

Identification of multiple isoforms of glucocorticoid receptor in nasal polyps of patients with chronic rhinosinusitis
gan: Shan Shao, et al.
Cyhoeddwyd: (2022-06-01)

Fungi as Causative Agents of Nasal Polyps in Tehran, Iran
gan: P Kordbacheh, et al.
Cyhoeddwyd: (2006-05-01)

Characterization of the Notch pathway in nasal polyps of patients with chronic rhinosinusitis: A pilot study
gan: Giorgio Aquila, et al.
Cyhoeddwyd: (2022-08-01)

Clinical and Histopathological Classification of Nasal Polyps in Thais
gan: Perapun Jareoncharsri, et al.
Cyhoeddwyd: (2002-11-01)

Local inflammatory marker production in Lithuanian patients with chronic rhinosinusitis with nasal polyps
gan: Justinas Vaitkus, et al.
Cyhoeddwyd: (2020-01-01)

Increased lipopolysaccharide content is positively correlated with glucocorticoid receptor‐beta expression in chronic rhinosinusitis with nasal polyps
gan: Shui‐Bin Wang, et al.
Cyhoeddwyd: (2020-12-01)

Antimicrobial and Defense Proteins in Chronic Rhinosinusitis with Nasal Polyps
gan: Rudolfs Janis Viksne, et al.
Cyhoeddwyd: (2023-07-01)

The roles of nasal nitric oxide in diagnosis and endotypes of chronic rhinosinusitis with nasal polyps
gan: Mengdi Zhu, et al.
Cyhoeddwyd: (2020-09-01)

PREVALENCE OF NASAL POLYPS IN CHRONIC RHINOSINUSITIS PATIENTS UNDERGOING FUNCTIONAL ENDOSCOPIC SINUS SURGERY
gan: Abdul Azeem Rasouli, et al.
Cyhoeddwyd: (2021-06-01)

PREVALENCE OF NASAL POLYPS IN CHRONIC RHINOSINUSITIS PATIENTS UNDERGOING FUNCTIONAL ENDOSCOPIC SINUS SURGERY
gan: Abdul Azeem Rasouli, et al.
Cyhoeddwyd: (2021-07-01)

Could Eosinophilia predict clinical severity in nasal polyps?
gan: Figen Aslan, et al.
Cyhoeddwyd: (2017-08-01)

Impact of mucosal biofilm and bony osteitis on chronic rhinosinusitis with nasal polyps
gan: Hassan El Ibiary, et al.
Cyhoeddwyd: (2020-09-01)

WDPCP Modulates Cilia Beating Through the MAPK/ERK Pathway in Chronic Rhinosinusitis With Nasal Polyps
gan: Yun Ma, et al.
Cyhoeddwyd: (2021-02-01)

Risk Prediction of Chronic Rhinosinusitis with or without Nasal Polyps in Taiwanese Population Using Polygenic Risk Score for Nasal Polyps
gan: Rong-San Jiang, et al.
Cyhoeddwyd: (2023-10-01)

Microbiome and Th cytokines association in chronic rhinosinusitis with or without nasal polyp
gan: ZhongShou Zhu, et al.
Cyhoeddwyd: (2023-04-01)

Visual and bibliometric analysis of chronic rhinosinusitis and nasal polyps
gan: Zhichen Liu, MD, et al.
Cyhoeddwyd: (2024-05-01)

Vitamin D decreases the secretion of eotaxin and RANTES in nasal polyp fibroblasts derived from Taiwanese patients with chronic rhinosinusitis with nasal polyps
gan: Ling-Feng Wang, et al.
Cyhoeddwyd: (2015-02-01)

Emerging Role of Proteases in the Pathogenesis of Chronic Rhinosinusitis with Nasal Polyps
gan: Dawei Wu, et al.
Cyhoeddwyd: (2018-01-01)

Serum Proteomic Analysis Revealed Biomarkers for Eosinophilic Chronic Rhinosinusitis with Nasal Polyps Pathophysiology
gan: Chen Y, et al.
Cyhoeddwyd: (2024-02-01)

Characterization of Cytokines and Proliferation Marker Ki67 in Chronic Rhinosinusitis with Nasal Polyps: A Pilot Study
gan: Rudolfs Janis Viksne, et al.
Cyhoeddwyd: (2021-06-01)

Real-World Cost of Nasal Polyps Surgery and Risk of Major Complications in the United States: A Descriptive Retrospective Database Analysis
gan: Ge W, et al.
Cyhoeddwyd: (2022-11-01)

The chronic rhinosinusitis with nasal polyp patient journey in the United States and Europe
gan: Jeremiah Hwee, et al.
Cyhoeddwyd: (2024-02-01)

Neutrophils Play an Important Role in the Recurrence of Chronic Rhinosinusitis with Nasal Polyps
gan: Hyunjae Yu, et al.
Cyhoeddwyd: (2022-11-01)

Endotypes of Asian chronic rhinosinusitis with nasal polyps: A narrative review
gan: Gwanghui Ryu, et al.
Cyhoeddwyd: (2022-09-01)

Predominant Endotype of Nasal Polyps in a Sample of Filipinos Following Endoscopic Sinus Surgery for Chronic Rhinosinusitis with Nasal Polyposis
gan: Karla Victoria Nable-Llanes, et al.
Cyhoeddwyd: (2021-05-01)

Dupilumab Improves Outcomes in Patients with Chronic Rhinosinusitis with Nasal Polyps and Coexisting Asthma Irrespective of Baseline Asthma Characteristics
gan: Busse WW, et al.
Cyhoeddwyd: (2023-04-01)

Update on the Biological and Clinical Relevance of Mast Cells in Chronic Rhinosinusitis with Nasal Polyps
gan: Luca Giovanni Locatello, et al.
Cyhoeddwyd: (2024-11-01)

Brazilian guideline for the use of immunobiologicals in chronic rhinosinusitis with nasal polyps ‒ 2024 update
gan: Wilma T. Anselmo-Lima, et al.
Cyhoeddwyd: (2024-05-01)

Cost-effectiveness analysis of biologics for the treatment of chronic rhinosinusitis with nasal polyps in Canada
gan: Michael Yong, et al.
Cyhoeddwyd: (2023-10-01)

Guideline for the use of immunobiologicals in chronic rhinosinusitis with nasal polyps (CRSwNP) in Brazil
gan: Wilma T. Anselmo-Lima, et al.
Cyhoeddwyd: (2022-05-01)

The Role of Serum Metabolomics in Distinguishing Chronic Rhinosinusitis With Nasal Polyp Phenotypes
gan: Shaobing Xie, et al.
Cyhoeddwyd: (2021-01-01)

Study of microbial factors in exacerbation of chronic rhinosinusitis with nasal polyps
gan: Elena L. Savlevich, et al.
Cyhoeddwyd: (2022-09-01)

Predicting the effectiveness of omalizumab in patients with refractory chronic rhinosinusitis with nasal polyps comorbid with asthma based on inflammatory biomarkers
gan: Yutong Sima, MD, et al.
Cyhoeddwyd: (2025-01-01)

MicroRNA-145-5p Regulates the Epithelial-Mesenchymal Transition in Nasal Polyps by Targeting Smad3
gan: Mengyu Zhang, et al.
Cyhoeddwyd: (2024-05-01)

Clinical Characteristics of Eosinophilic Chronic Rhinosinusitis with Nasal Polyps in Adolescents
gan: Huang CC, et al.
Cyhoeddwyd: (2023-10-01)

Nasal polyps and its histopathological classification: A retrospective study
gan: Jitendra Pratap Singh Chauhan, et al.
Cyhoeddwyd: (2023-08-01)

Peak nasal inspiratory flow assessment of polyp size and response from SYNAPSE
gan: Amber U. Luong, MD, PhD, et al.
Cyhoeddwyd: (2024-11-01)

A diagnostic model for predicting type 2 nasal polyps using biomarkers in nasal secretion
gan: Zaichuan Wang, et al.
Cyhoeddwyd: (2022-12-01)

Decrease in number of mast cells in resected nasal polyps as an indicator for postoperative recurrence of chronic rhinosinusitis
gan: Yuichi Teranishi, et al.
Cyhoeddwyd: (2019-09-01)