Transcriptomic and Lipidomic Profiles in Nasal Polyps of Glucocorticoid Responders and Non-Responders: Before and After Treatment

Transcriptomic and Lipidomic Profiles in Nasal Polyps of Glucocorticoid Responders and Non-Responders: Before and After Treatment

Background: The pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) and mechanisms underlying different responses to systemic glucocorticoids (GC) remain unclear. The major aim of this study was to explore the transcriptomic and oxidative lipidomic signatures and the effects of GC in p...

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Bibliografiske detaljer
Main Authors:	Zhenzhen Zhu, Weiqing Wang, Yang Zha, Xiaowei Wang, Lei Wang, Jinbo Han, Jianmin Zhang, Wei Lv
Format:	Article
Sprog:	English
Udgivet:	Frontiers Media S.A. 2022-01-01
Serier:	Frontiers in Pharmacology
Fag:	chronic rhinosinusitis with nasal polyps cilia glucocorticoids oxylipid mediator transcriptomic sequencing
Online adgang:	https://www.frontiersin.org/articles/10.3389/fphar.2021.814953/full

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