Transcriptomic and Lipidomic Profiles in Nasal Polyps of Glucocorticoid Responders and Non-Responders: Before and After Treatment

Transcriptomic and Lipidomic Profiles in Nasal Polyps of Glucocorticoid Responders and Non-Responders: Before and After Treatment

Background: The pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) and mechanisms underlying different responses to systemic glucocorticoids (GC) remain unclear. The major aim of this study was to explore the transcriptomic and oxidative lipidomic signatures and the effects of GC in p...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Zhenzhen Zhu, Weiqing Wang, Yang Zha, Xiaowei Wang, Lei Wang, Jinbo Han, Jianmin Zhang, Wei Lv
Formáid:	Alt
Teanga:	English
Foilsithe / Cruthaithe:	Frontiers Media S.A. 2022-01-01
Sraith:	Frontiers in Pharmacology
Ábhair:	chronic rhinosinusitis with nasal polyps cilia glucocorticoids oxylipid mediator transcriptomic sequencing
Rochtain ar líne:	https://www.frontiersin.org/articles/10.3389/fphar.2021.814953/full

Míreanna comhchosúla

Effect of short-course glucocorticoid application on patients with chronic rhinosinusitis with nasal polyps
de réir: Zhaofeng Xu, et al.
Foilsithe / Cruthaithe: (2020-06-01)

Identification of multiple isoforms of glucocorticoid receptor in nasal polyps of patients with chronic rhinosinusitis
de réir: Shan Shao, et al.
Foilsithe / Cruthaithe: (2022-06-01)

Fungi as Causative Agents of Nasal Polyps in Tehran, Iran
de réir: P Kordbacheh, et al.
Foilsithe / Cruthaithe: (2006-05-01)

Characterization of the Notch pathway in nasal polyps of patients with chronic rhinosinusitis: A pilot study
de réir: Giorgio Aquila, et al.
Foilsithe / Cruthaithe: (2022-08-01)

Clinical and Histopathological Classification of Nasal Polyps in Thais
de réir: Perapun Jareoncharsri, et al.
Foilsithe / Cruthaithe: (2002-11-01)

Local inflammatory marker production in Lithuanian patients with chronic rhinosinusitis with nasal polyps
de réir: Justinas Vaitkus, et al.
Foilsithe / Cruthaithe: (2020-01-01)

Increased lipopolysaccharide content is positively correlated with glucocorticoid receptor‐beta expression in chronic rhinosinusitis with nasal polyps
de réir: Shui‐Bin Wang, et al.
Foilsithe / Cruthaithe: (2020-12-01)

Antimicrobial and Defense Proteins in Chronic Rhinosinusitis with Nasal Polyps
de réir: Rudolfs Janis Viksne, et al.
Foilsithe / Cruthaithe: (2023-07-01)

The roles of nasal nitric oxide in diagnosis and endotypes of chronic rhinosinusitis with nasal polyps
de réir: Mengdi Zhu, et al.
Foilsithe / Cruthaithe: (2020-09-01)

PREVALENCE OF NASAL POLYPS IN CHRONIC RHINOSINUSITIS PATIENTS UNDERGOING FUNCTIONAL ENDOSCOPIC SINUS SURGERY
de réir: Abdul Azeem Rasouli, et al.
Foilsithe / Cruthaithe: (2021-06-01)

PREVALENCE OF NASAL POLYPS IN CHRONIC RHINOSINUSITIS PATIENTS UNDERGOING FUNCTIONAL ENDOSCOPIC SINUS SURGERY
de réir: Abdul Azeem Rasouli, et al.
Foilsithe / Cruthaithe: (2021-07-01)

Could Eosinophilia predict clinical severity in nasal polyps?
de réir: Figen Aslan, et al.
Foilsithe / Cruthaithe: (2017-08-01)

Impact of mucosal biofilm and bony osteitis on chronic rhinosinusitis with nasal polyps
de réir: Hassan El Ibiary, et al.
Foilsithe / Cruthaithe: (2020-09-01)

WDPCP Modulates Cilia Beating Through the MAPK/ERK Pathway in Chronic Rhinosinusitis With Nasal Polyps
de réir: Yun Ma, et al.
Foilsithe / Cruthaithe: (2021-02-01)

Risk Prediction of Chronic Rhinosinusitis with or without Nasal Polyps in Taiwanese Population Using Polygenic Risk Score for Nasal Polyps
de réir: Rong-San Jiang, et al.
Foilsithe / Cruthaithe: (2023-10-01)

Microbiome and Th cytokines association in chronic rhinosinusitis with or without nasal polyp
de réir: ZhongShou Zhu, et al.
Foilsithe / Cruthaithe: (2023-04-01)

Visual and bibliometric analysis of chronic rhinosinusitis and nasal polyps
de réir: Zhichen Liu, MD, et al.
Foilsithe / Cruthaithe: (2024-05-01)

Vitamin D decreases the secretion of eotaxin and RANTES in nasal polyp fibroblasts derived from Taiwanese patients with chronic rhinosinusitis with nasal polyps
de réir: Ling-Feng Wang, et al.
Foilsithe / Cruthaithe: (2015-02-01)

Emerging Role of Proteases in the Pathogenesis of Chronic Rhinosinusitis with Nasal Polyps
de réir: Dawei Wu, et al.
Foilsithe / Cruthaithe: (2018-01-01)

Serum Proteomic Analysis Revealed Biomarkers for Eosinophilic Chronic Rhinosinusitis with Nasal Polyps Pathophysiology
de réir: Chen Y, et al.
Foilsithe / Cruthaithe: (2024-02-01)

Characterization of Cytokines and Proliferation Marker Ki67 in Chronic Rhinosinusitis with Nasal Polyps: A Pilot Study
de réir: Rudolfs Janis Viksne, et al.
Foilsithe / Cruthaithe: (2021-06-01)

Real-World Cost of Nasal Polyps Surgery and Risk of Major Complications in the United States: A Descriptive Retrospective Database Analysis
de réir: Ge W, et al.
Foilsithe / Cruthaithe: (2022-11-01)

The chronic rhinosinusitis with nasal polyp patient journey in the United States and Europe
de réir: Jeremiah Hwee, et al.
Foilsithe / Cruthaithe: (2024-02-01)

Neutrophils Play an Important Role in the Recurrence of Chronic Rhinosinusitis with Nasal Polyps
de réir: Hyunjae Yu, et al.
Foilsithe / Cruthaithe: (2022-11-01)

Endotypes of Asian chronic rhinosinusitis with nasal polyps: A narrative review
de réir: Gwanghui Ryu, et al.
Foilsithe / Cruthaithe: (2022-09-01)

Predominant Endotype of Nasal Polyps in a Sample of Filipinos Following Endoscopic Sinus Surgery for Chronic Rhinosinusitis with Nasal Polyposis
de réir: Karla Victoria Nable-Llanes, et al.
Foilsithe / Cruthaithe: (2021-05-01)

Dupilumab Improves Outcomes in Patients with Chronic Rhinosinusitis with Nasal Polyps and Coexisting Asthma Irrespective of Baseline Asthma Characteristics
de réir: Busse WW, et al.
Foilsithe / Cruthaithe: (2023-04-01)

Update on the Biological and Clinical Relevance of Mast Cells in Chronic Rhinosinusitis with Nasal Polyps
de réir: Luca Giovanni Locatello, et al.
Foilsithe / Cruthaithe: (2024-11-01)

Brazilian guideline for the use of immunobiologicals in chronic rhinosinusitis with nasal polyps ‒ 2024 update
de réir: Wilma T. Anselmo-Lima, et al.
Foilsithe / Cruthaithe: (2024-05-01)

Cost-effectiveness analysis of biologics for the treatment of chronic rhinosinusitis with nasal polyps in Canada
de réir: Michael Yong, et al.
Foilsithe / Cruthaithe: (2023-10-01)

Guideline for the use of immunobiologicals in chronic rhinosinusitis with nasal polyps (CRSwNP) in Brazil
de réir: Wilma T. Anselmo-Lima, et al.
Foilsithe / Cruthaithe: (2022-05-01)

The Role of Serum Metabolomics in Distinguishing Chronic Rhinosinusitis With Nasal Polyp Phenotypes
de réir: Shaobing Xie, et al.
Foilsithe / Cruthaithe: (2021-01-01)

Study of microbial factors in exacerbation of chronic rhinosinusitis with nasal polyps
de réir: Elena L. Savlevich, et al.
Foilsithe / Cruthaithe: (2022-09-01)

Predicting the effectiveness of omalizumab in patients with refractory chronic rhinosinusitis with nasal polyps comorbid with asthma based on inflammatory biomarkers
de réir: Yutong Sima, MD, et al.
Foilsithe / Cruthaithe: (2025-01-01)

MicroRNA-145-5p Regulates the Epithelial-Mesenchymal Transition in Nasal Polyps by Targeting Smad3
de réir: Mengyu Zhang, et al.
Foilsithe / Cruthaithe: (2024-05-01)

Clinical Characteristics of Eosinophilic Chronic Rhinosinusitis with Nasal Polyps in Adolescents
de réir: Huang CC, et al.
Foilsithe / Cruthaithe: (2023-10-01)

Nasal polyps and its histopathological classification: A retrospective study
de réir: Jitendra Pratap Singh Chauhan, et al.
Foilsithe / Cruthaithe: (2023-08-01)

Peak nasal inspiratory flow assessment of polyp size and response from SYNAPSE
de réir: Amber U. Luong, MD, PhD, et al.
Foilsithe / Cruthaithe: (2024-11-01)

A diagnostic model for predicting type 2 nasal polyps using biomarkers in nasal secretion
de réir: Zaichuan Wang, et al.
Foilsithe / Cruthaithe: (2022-12-01)

Decrease in number of mast cells in resected nasal polyps as an indicator for postoperative recurrence of chronic rhinosinusitis
de réir: Yuichi Teranishi, et al.
Foilsithe / Cruthaithe: (2019-09-01)