Transcriptomic and Lipidomic Profiles in Nasal Polyps of Glucocorticoid Responders and Non-Responders: Before and After Treatment

Transcriptomic and Lipidomic Profiles in Nasal Polyps of Glucocorticoid Responders and Non-Responders: Before and After Treatment

Background: The pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) and mechanisms underlying different responses to systemic glucocorticoids (GC) remain unclear. The major aim of this study was to explore the transcriptomic and oxidative lipidomic signatures and the effects of GC in p...

Descripció completa

Dades bibliogràfiques
Autors principals: Zhenzhen Zhu, Weiqing Wang, Yang Zha, Xiaowei Wang, Lei Wang, Jinbo Han, Jianmin Zhang, Wei Lv
Format: Article
Idioma:English
Publicat: Frontiers Media S.A. 2022-01-01
Col·lecció:Frontiers in Pharmacology
Matèries:
chronic rhinosinusitis with nasal polyps
cilia
glucocorticoids
oxylipid mediator
transcriptomic sequencing
Accés en línia:https://www.frontiersin.org/articles/10.3389/fphar.2021.814953/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.814953/full

Ítems similars