Analysis of fundus shape in highly myopic eyes by using curvature maps constructed from optical coherence tomography.
PURPOSE: To evaluate fundus shape in highly myopic eyes using color maps created through optical coherence tomography (OCT) image analysis. METHODS: We retrospectively evaluated 182 highly myopic eyes from 113 patients. After obtaining 12 lines of 9-mm radial OCT scans with the fovea at the center,...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4178042?pdf=render |
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| author | Masahiro Miyake Kenji Yamashiro Yumiko Akagi-Kurashige Akio Oishi Akitaka Tsujikawa Masanori Hangai Nagahisa Yoshimura |
| author_facet | Masahiro Miyake Kenji Yamashiro Yumiko Akagi-Kurashige Akio Oishi Akitaka Tsujikawa Masanori Hangai Nagahisa Yoshimura |
| author_sort | Masahiro Miyake |
| collection | DOAJ |
| description | PURPOSE: To evaluate fundus shape in highly myopic eyes using color maps created through optical coherence tomography (OCT) image analysis. METHODS: We retrospectively evaluated 182 highly myopic eyes from 113 patients. After obtaining 12 lines of 9-mm radial OCT scans with the fovea at the center, the Bruch's membrane line was plotted and its curvature was measured at 1-µm intervals in each image, which was reflected as a color topography map. For the quantitative analysis of the eye shape, mean absolute curvature and variance of curvature were calculated. RESULTS: The color maps allowed staphyloma visualization as a ring of green color at the edge and as that of orange-red color at the bottom. Analyses of mean and variance of curvature revealed that eyes with myopic choroidal neovascularization tended to have relatively flat posterior poles with smooth surfaces, while eyes with chorioretinal atrophy exhibited a steep, curved shape with an undulated surface (P<0.001). Furthermore, eyes with staphylomas and those without clearly differed in terms of mean curvature and the variance of curvature: 98.4% of eyes with staphylomas had mean curvature ≥7.8×10-5 [1/µm] and variance of curvature ≥0.26×10-8 [1/µm]. CONCLUSIONS: We established a novel method to analyze posterior pole shape by using OCT images to construct curvature maps. Our quantitative analysis revealed that fundus shape is associated with myopic complications. These values were also effective in distinguishing eyes with staphylomas from those without. This tool for the quantitative evaluation of eye shape should facilitate future research of myopic complications. |
| first_indexed | 2024-12-22T13:54:23Z |
| format | Article |
| id | doaj.art-a84fb23d15384ef98a5f088f686e065f |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-22T13:54:23Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-a84fb23d15384ef98a5f088f686e065f2022-12-21T18:23:35ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0199e10792310.1371/journal.pone.0107923Analysis of fundus shape in highly myopic eyes by using curvature maps constructed from optical coherence tomography.Masahiro MiyakeKenji YamashiroYumiko Akagi-KurashigeAkio OishiAkitaka TsujikawaMasanori HangaiNagahisa YoshimuraPURPOSE: To evaluate fundus shape in highly myopic eyes using color maps created through optical coherence tomography (OCT) image analysis. METHODS: We retrospectively evaluated 182 highly myopic eyes from 113 patients. After obtaining 12 lines of 9-mm radial OCT scans with the fovea at the center, the Bruch's membrane line was plotted and its curvature was measured at 1-µm intervals in each image, which was reflected as a color topography map. For the quantitative analysis of the eye shape, mean absolute curvature and variance of curvature were calculated. RESULTS: The color maps allowed staphyloma visualization as a ring of green color at the edge and as that of orange-red color at the bottom. Analyses of mean and variance of curvature revealed that eyes with myopic choroidal neovascularization tended to have relatively flat posterior poles with smooth surfaces, while eyes with chorioretinal atrophy exhibited a steep, curved shape with an undulated surface (P<0.001). Furthermore, eyes with staphylomas and those without clearly differed in terms of mean curvature and the variance of curvature: 98.4% of eyes with staphylomas had mean curvature ≥7.8×10-5 [1/µm] and variance of curvature ≥0.26×10-8 [1/µm]. CONCLUSIONS: We established a novel method to analyze posterior pole shape by using OCT images to construct curvature maps. Our quantitative analysis revealed that fundus shape is associated with myopic complications. These values were also effective in distinguishing eyes with staphylomas from those without. This tool for the quantitative evaluation of eye shape should facilitate future research of myopic complications.http://europepmc.org/articles/PMC4178042?pdf=render |
| spellingShingle | Masahiro Miyake Kenji Yamashiro Yumiko Akagi-Kurashige Akio Oishi Akitaka Tsujikawa Masanori Hangai Nagahisa Yoshimura Analysis of fundus shape in highly myopic eyes by using curvature maps constructed from optical coherence tomography. PLoS ONE |
| title | Analysis of fundus shape in highly myopic eyes by using curvature maps constructed from optical coherence tomography. |
| title_full | Analysis of fundus shape in highly myopic eyes by using curvature maps constructed from optical coherence tomography. |
| title_fullStr | Analysis of fundus shape in highly myopic eyes by using curvature maps constructed from optical coherence tomography. |
| title_full_unstemmed | Analysis of fundus shape in highly myopic eyes by using curvature maps constructed from optical coherence tomography. |
| title_short | Analysis of fundus shape in highly myopic eyes by using curvature maps constructed from optical coherence tomography. |
| title_sort | analysis of fundus shape in highly myopic eyes by using curvature maps constructed from optical coherence tomography |
| url | http://europepmc.org/articles/PMC4178042?pdf=render |
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