Inhibitory Effect of Hydroxymethylfurfural in Viability of BALB/C Mice Splenocytes

Inhibitory Effect of Hydroxymethylfurfural in Viability of BALB/C Mice Splenocytes

Background: This study was designed to discover if hydroxymethylfurfural (HMF) exposure modifies cell proliferation and DNA damage in BALB/c mice splenocytes. Methods: Mitogenesis in T cells and B cells was induced by Concanavalin A (Con A) and lipopolysaccharide (LPS). The colorimetric tetrazolium...

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Bibliographic Details
Main Authors: Sevda Saleh-Ghadimi, Hamed Jafari-Vayghan, Sorayya Kheirouri, Mohammad Alizadeh
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2019-03-01
Series:Pharmaceutical Sciences
Subjects:
DNA damage
Hydroxymethylfurfural
Mutagenicity
Splenocyte
Online Access:https://ps.tbzmed.ac.ir/PDF/PHARM_26162_20180901000333

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