Diagnosing dementia in the Arctic: translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland Inuit
Introduction The ageing Arctic populations raise the need for work-up of cognitive function that reflects language and cultural understandings. Objectives To translate and evaluate tools for work-up of cognitive impairment in Greenland. Methods Step A: An expert panel was established to select to...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2022-06-01
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| Series: | European Psychiatry |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S092493382200459X/type/journal_article |
| _version_ | 1827754536805072896 |
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| author | I. Kleist P. Noahsen O. Gredal J. Riis S. Andersen |
| author_facet | I. Kleist P. Noahsen O. Gredal J. Riis S. Andersen |
| author_sort | I. Kleist |
| collection | DOAJ |
| description |
Introduction
The ageing Arctic populations raise the need for work-up of cognitive function that reflects language and cultural understandings.
Objectives
To translate and evaluate tools for work-up of cognitive impairment in Greenland.
Methods
Step A: An expert panel was established to select tools suitable for the work-up of cognitive impairment at three different settings in Greenland. Step B: Tools were translated in a multiple-step process of independent translations with back-translation and adaptations by two independent translators and two Greenlandic physicians. Step C: a testing and validation process of the tools at three locations: the national hospital in the capital city; regional hospital in a town; health care centre in a small town.
Results
Tools selected were Mini-Cog and RUDAS. Participants for testing of tools were 43 of 61 invited, of which six had dementia. RUDAS and Mini-Cog scores were associated (p < 0.001). The smoothed AUC was 0.87 (95%-CI, 0.65–0.95) for Mini-Cog and 0.90 (95%-CI, 0.76–0.97) for RUDAS. The sensitivity of Mini-Cog with a cut-off at ≤3 was 83.3%, and specificity was 62.2%. For RUDAS with a cut-off at ≤23, these were 100% and 75.7%, respectively.
Conclusions
Requested tools have been translated for assessing cognitive function in the native Arctic setting. Small town residents with a Mini-Cog score of 3 or lower should be referred to a regional hospital for RUDAS, and a score of 23 or less should cause referral to the national hospital for a full work-up of cognitive function.
Disclosure
No significant relationships.
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| first_indexed | 2024-03-11T07:50:45Z |
| format | Article |
| id | doaj.art-a852f3dfa3a24e95868968e622a39ee8 |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-03-11T07:50:45Z |
| publishDate | 2022-06-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-a852f3dfa3a24e95868968e622a39ee82023-11-17T05:06:47ZengCambridge University PressEuropean Psychiatry0924-93381778-35852022-06-0165S173S17310.1192/j.eurpsy.2022.459Diagnosing dementia in the Arctic: translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland InuitI. Kleist0P. Noahsen1O. Gredal2J. Riis3S. Andersen4Aarhus University Hospital, Forensic Psychiatric, Aarhus N, DenmarkeNational Board of Health in Greenland, Enational Board Of Health In Greenland, Nuuk, GreenlandQueen Ingrid’s Hospital, Nuuk, Greenland, Department Of Internal Medicine, Nuuk, GreenlandAalborg University Hospital, Department Of Geriatric Medicine,, Aalborg, DenmarkAalborg University Hospital, Department Of Geriatric Medicine,, Aalborg, Denmark Introduction The ageing Arctic populations raise the need for work-up of cognitive function that reflects language and cultural understandings. Objectives To translate and evaluate tools for work-up of cognitive impairment in Greenland. Methods Step A: An expert panel was established to select tools suitable for the work-up of cognitive impairment at three different settings in Greenland. Step B: Tools were translated in a multiple-step process of independent translations with back-translation and adaptations by two independent translators and two Greenlandic physicians. Step C: a testing and validation process of the tools at three locations: the national hospital in the capital city; regional hospital in a town; health care centre in a small town. Results Tools selected were Mini-Cog and RUDAS. Participants for testing of tools were 43 of 61 invited, of which six had dementia. RUDAS and Mini-Cog scores were associated (p < 0.001). The smoothed AUC was 0.87 (95%-CI, 0.65–0.95) for Mini-Cog and 0.90 (95%-CI, 0.76–0.97) for RUDAS. The sensitivity of Mini-Cog with a cut-off at ≤3 was 83.3%, and specificity was 62.2%. For RUDAS with a cut-off at ≤23, these were 100% and 75.7%, respectively. Conclusions Requested tools have been translated for assessing cognitive function in the native Arctic setting. Small town residents with a Mini-Cog score of 3 or lower should be referred to a regional hospital for RUDAS, and a score of 23 or less should cause referral to the national hospital for a full work-up of cognitive function. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S092493382200459X/type/journal_articlemini-cogDementiaRUDAScognitive function |
| spellingShingle | I. Kleist P. Noahsen O. Gredal J. Riis S. Andersen Diagnosing dementia in the Arctic: translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland Inuit European Psychiatry mini-cog Dementia RUDAS cognitive function |
| title | Diagnosing dementia in the Arctic: translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland Inuit |
| title_full | Diagnosing dementia in the Arctic: translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland Inuit |
| title_fullStr | Diagnosing dementia in the Arctic: translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland Inuit |
| title_full_unstemmed | Diagnosing dementia in the Arctic: translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland Inuit |
| title_short | Diagnosing dementia in the Arctic: translating tools and developing and validating an algorithm for assessment of impaired cognitive function in Greenland Inuit |
| title_sort | diagnosing dementia in the arctic translating tools and developing and validating an algorithm for assessment of impaired cognitive function in greenland inuit |
| topic | mini-cog Dementia RUDAS cognitive function |
| url | https://www.cambridge.org/core/product/identifier/S092493382200459X/type/journal_article |
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