How to Make the Right Diagnosis in Neutropenia

Isolated neutropenia without anemia or thrombocytopenia is a common clinical problem. The etiology of neutropenia may vary from transient bone marrow suppression, caused by self-limited viral illnesses, to previously undiagnosed congenital syndromes or serious systemic diseases. Consequently, determ...

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Main Authors: Elena E. Solomou, Christina Salamaliki, Maria Lagadinou
Format: Article
Language:English
Published: SAABRON PRESS 2021-02-01
Series:Clinical Hematology International
Subjects:
Online Access:https://www.atlantis-press.com/article/125953238/view
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author Elena E. Solomou
Christina Salamaliki
Maria Lagadinou
author_facet Elena E. Solomou
Christina Salamaliki
Maria Lagadinou
author_sort Elena E. Solomou
collection DOAJ
description Isolated neutropenia without anemia or thrombocytopenia is a common clinical problem. The etiology of neutropenia may vary from transient bone marrow suppression, caused by self-limited viral illnesses, to previously undiagnosed congenital syndromes or serious systemic diseases. Consequently, determining the underlying cause of neutropenia and what treatment is required can be challenging. Acquired neutropenia is common and most of the times an etiologic factor can be found. Congenital neutropenia (CN) is rare, and we still have a lot to learn from mutational analysis as to the exact role of gene abnormalities in the pathogenesis of these complex diseases. This mini-review discusses a proposed approach to neutropenia in the adult patient.
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spelling doaj.art-a856ca0150cd445f915074c4e94ac8fa2024-04-02T10:44:02ZengSAABRON PRESSClinical Hematology International2590-00482021-02-013210.2991/chi.k.210216.001How to Make the Right Diagnosis in NeutropeniaElena E. SolomouChristina SalamalikiMaria LagadinouIsolated neutropenia without anemia or thrombocytopenia is a common clinical problem. The etiology of neutropenia may vary from transient bone marrow suppression, caused by self-limited viral illnesses, to previously undiagnosed congenital syndromes or serious systemic diseases. Consequently, determining the underlying cause of neutropenia and what treatment is required can be challenging. Acquired neutropenia is common and most of the times an etiologic factor can be found. Congenital neutropenia (CN) is rare, and we still have a lot to learn from mutational analysis as to the exact role of gene abnormalities in the pathogenesis of these complex diseases. This mini-review discusses a proposed approach to neutropenia in the adult patient.https://www.atlantis-press.com/article/125953238/viewNeutropeniainfectionsdrugsdifferential diagnosis
spellingShingle Elena E. Solomou
Christina Salamaliki
Maria Lagadinou
How to Make the Right Diagnosis in Neutropenia
Clinical Hematology International
Neutropenia
infections
drugs
differential diagnosis
title How to Make the Right Diagnosis in Neutropenia
title_full How to Make the Right Diagnosis in Neutropenia
title_fullStr How to Make the Right Diagnosis in Neutropenia
title_full_unstemmed How to Make the Right Diagnosis in Neutropenia
title_short How to Make the Right Diagnosis in Neutropenia
title_sort how to make the right diagnosis in neutropenia
topic Neutropenia
infections
drugs
differential diagnosis
url https://www.atlantis-press.com/article/125953238/view
work_keys_str_mv AT elenaesolomou howtomaketherightdiagnosisinneutropenia
AT christinasalamaliki howtomaketherightdiagnosisinneutropenia
AT marialagadinou howtomaketherightdiagnosisinneutropenia