How to Make the Right Diagnosis in Neutropenia
Isolated neutropenia without anemia or thrombocytopenia is a common clinical problem. The etiology of neutropenia may vary from transient bone marrow suppression, caused by self-limited viral illnesses, to previously undiagnosed congenital syndromes or serious systemic diseases. Consequently, determ...
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Format: | Article |
Language: | English |
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SAABRON PRESS
2021-02-01
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Series: | Clinical Hematology International |
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Online Access: | https://www.atlantis-press.com/article/125953238/view |
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author | Elena E. Solomou Christina Salamaliki Maria Lagadinou |
author_facet | Elena E. Solomou Christina Salamaliki Maria Lagadinou |
author_sort | Elena E. Solomou |
collection | DOAJ |
description | Isolated neutropenia without anemia or thrombocytopenia is a common clinical problem. The etiology of neutropenia may vary from transient bone marrow suppression, caused by self-limited viral illnesses, to previously undiagnosed congenital syndromes or serious systemic diseases. Consequently, determining the underlying cause of neutropenia and what treatment is required can be challenging. Acquired neutropenia is common and most of the times an etiologic factor can be found. Congenital neutropenia (CN) is rare, and we still have a lot to learn from mutational analysis as to the exact role of gene abnormalities in the pathogenesis of these complex diseases. This mini-review discusses a proposed approach to neutropenia in the adult patient. |
first_indexed | 2024-04-24T15:11:59Z |
format | Article |
id | doaj.art-a856ca0150cd445f915074c4e94ac8fa |
institution | Directory Open Access Journal |
issn | 2590-0048 |
language | English |
last_indexed | 2024-04-24T15:11:59Z |
publishDate | 2021-02-01 |
publisher | SAABRON PRESS |
record_format | Article |
series | Clinical Hematology International |
spelling | doaj.art-a856ca0150cd445f915074c4e94ac8fa2024-04-02T10:44:02ZengSAABRON PRESSClinical Hematology International2590-00482021-02-013210.2991/chi.k.210216.001How to Make the Right Diagnosis in NeutropeniaElena E. SolomouChristina SalamalikiMaria LagadinouIsolated neutropenia without anemia or thrombocytopenia is a common clinical problem. The etiology of neutropenia may vary from transient bone marrow suppression, caused by self-limited viral illnesses, to previously undiagnosed congenital syndromes or serious systemic diseases. Consequently, determining the underlying cause of neutropenia and what treatment is required can be challenging. Acquired neutropenia is common and most of the times an etiologic factor can be found. Congenital neutropenia (CN) is rare, and we still have a lot to learn from mutational analysis as to the exact role of gene abnormalities in the pathogenesis of these complex diseases. This mini-review discusses a proposed approach to neutropenia in the adult patient.https://www.atlantis-press.com/article/125953238/viewNeutropeniainfectionsdrugsdifferential diagnosis |
spellingShingle | Elena E. Solomou Christina Salamaliki Maria Lagadinou How to Make the Right Diagnosis in Neutropenia Clinical Hematology International Neutropenia infections drugs differential diagnosis |
title | How to Make the Right Diagnosis in Neutropenia |
title_full | How to Make the Right Diagnosis in Neutropenia |
title_fullStr | How to Make the Right Diagnosis in Neutropenia |
title_full_unstemmed | How to Make the Right Diagnosis in Neutropenia |
title_short | How to Make the Right Diagnosis in Neutropenia |
title_sort | how to make the right diagnosis in neutropenia |
topic | Neutropenia infections drugs differential diagnosis |
url | https://www.atlantis-press.com/article/125953238/view |
work_keys_str_mv | AT elenaesolomou howtomaketherightdiagnosisinneutropenia AT christinasalamaliki howtomaketherightdiagnosisinneutropenia AT marialagadinou howtomaketherightdiagnosisinneutropenia |