Role of viral infection in the etiopathogenesis of breast cancer

The viral nature of many female genital cancers is now beyond question; however, the role of viral infection in the pathogenesis of breast cancer (BC) has not been adequately investigated. The paper defines the importance of a number of viruses in the etiopathogenesis of on- cogynecological diseases...

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Main Authors: L. A. Ashrafyan, V. K. Bozhenko, A. V. Slonov, O. A. Ovchinnikova, L. Z. Khunova
Format: Article
Language:Russian
Published: ABV-press 2014-08-01
Series:Опухоли женской репродуктивной системы
Subjects:
Online Access:https://ojrs.abvpress.ru/ojrs/article/view/251
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author L. A. Ashrafyan
V. K. Bozhenko
A. V. Slonov
O. A. Ovchinnikova
L. Z. Khunova
author_facet L. A. Ashrafyan
V. K. Bozhenko
A. V. Slonov
O. A. Ovchinnikova
L. Z. Khunova
author_sort L. A. Ashrafyan
collection DOAJ
description The viral nature of many female genital cancers is now beyond question; however, the role of viral infection in the pathogenesis of breast cancer (BC) has not been adequately investigated. The paper defines the importance of a number of viruses in the etiopathogenesis of on- cogynecological diseases. It presents the results of examining 60 patients with Stages I-IV BC and 30 patients with fibrocystic mastopathy, in whom the presence of DNA-containing virus genomes in tumor tissue was compared, and the data of polymerase chain reaction study of genital tract smears. It is shown that human papillomaviruses and cytomegaloviruses do not play a fundamental role in the develop- ment of BC; there is no valid evidence for Epstein–Barr virus.
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spelling doaj.art-a856f83f8f0445a8b2746f7e30f253252025-03-02T13:05:30ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272014-08-0103576110.17650/1994-4098-2010-0-3-57-61267Role of viral infection in the etiopathogenesis of breast cancerL. A. Ashrafyan0V. K. Bozhenko1A. V. Slonov2O. A. Ovchinnikova3L. Z. Khunova4Department of Gynecology, Russian X-Ray Radiology Research Center, Ministry of Health and Social Development, MoscowDepartment of Gynecology, Russian X-Ray Radiology Research Center, Ministry of Health and Social Development, MoscowDepartment of Gynecology, Russian X-Ray Radiology Research Center, Ministry of Health and Social Development, MoscowDepartment of Gynecology, Russian X-Ray Radiology Research Center, Ministry of Health and Social Development, MoscowDepartment of Gynecology, Russian X-Ray Radiology Research Center, Ministry of Health and Social Development, MoscowThe viral nature of many female genital cancers is now beyond question; however, the role of viral infection in the pathogenesis of breast cancer (BC) has not been adequately investigated. The paper defines the importance of a number of viruses in the etiopathogenesis of on- cogynecological diseases. It presents the results of examining 60 patients with Stages I-IV BC and 30 patients with fibrocystic mastopathy, in whom the presence of DNA-containing virus genomes in tumor tissue was compared, and the data of polymerase chain reaction study of genital tract smears. It is shown that human papillomaviruses and cytomegaloviruses do not play a fundamental role in the develop- ment of BC; there is no valid evidence for Epstein–Barr virus.https://ojrs.abvpress.ru/ojrs/article/view/251breast cancerhuman papillomavirusepstein-barr virusmouse mammary tumor virus
spellingShingle L. A. Ashrafyan
V. K. Bozhenko
A. V. Slonov
O. A. Ovchinnikova
L. Z. Khunova
Role of viral infection in the etiopathogenesis of breast cancer
Опухоли женской репродуктивной системы
breast cancer
human papillomavirus
epstein-barr virus
mouse mammary tumor virus
title Role of viral infection in the etiopathogenesis of breast cancer
title_full Role of viral infection in the etiopathogenesis of breast cancer
title_fullStr Role of viral infection in the etiopathogenesis of breast cancer
title_full_unstemmed Role of viral infection in the etiopathogenesis of breast cancer
title_short Role of viral infection in the etiopathogenesis of breast cancer
title_sort role of viral infection in the etiopathogenesis of breast cancer
topic breast cancer
human papillomavirus
epstein-barr virus
mouse mammary tumor virus
url https://ojrs.abvpress.ru/ojrs/article/view/251
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