The Marine-Derived Triterpenoid Frondoside A Inhibits Thrombus Formation

The Marine-Derived Triterpenoid Frondoside A Inhibits Thrombus Formation

Background: The marine-derived triterpenoid frondoside A inhibits the phosphatidylinositol-3-kinase (PI3K) pathway in cancer cells. Because this pathway is also crucially involved in platelet activation, we studied the effect of frondoside A on thrombus formation. Methods: Frondoside A effects on pl...

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Bibliographic Details
Main Authors: Emmanuel Ampofo, Thomas Später, Lisa Nalbach, Michael D. Menger, Matthias W. Laschke
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Marine Drugs
Subjects:
frondoside a
thrombus formation
thrombosis
hemostasis
platelets
pi3k
dorsal skinfold chamber
Online Access:https://www.mdpi.com/1660-3397/18/2/111

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